Benzylpenicilloyl polylysine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Benzylpenicilloyl polylysine
Benzylpenicilloyl polylysine (structural diagram).png
Clinical data
Trade names Pre-Pen
License data
Routes of
administration
Liquid intradermal
ATC code
  • none
Legal status
Legal status
Identifiers
Synonyms Pre-Pen
CAS Number
DrugBank
ChemSpider
  • none
ChEMBL
 NYesY (what is this?)  (verify)

Benzylpenicilloyl polylysine (Pre-Pen) is used as a skin test before the administration of penicillin. It is used to detect the immunoglobulin E antibodies.[1][2] The chemical structure consists of the benzylpenicilloyl group attached to a polymer of L-lysine.[3][4][5]

References[edit]

  1. ^ http://www.pharmgkb.org/do/serve?objId=PA164754810&objCls=Drug
  2. ^ http://www.drugbank.ca/drugs/DB00895
  3. ^ Vemuri, Preeti; Harris, Kathleen E.; Suh, Lydia A.; Grammer, Leslie C. (2004). "Preparation of benzylpenicilloyl-polylysine: a preliminary study". Allergy and Asthma Proceedings. 25 (3): 165–168. 
  4. ^ Goldschmidt, BM; BB Levine (1983). "The preparation and determination of structure of benzylpenicilloyl compounds used in skin-testing for penicillin allergy.". Journal of Antibiotics. 36 (6): 709–14. doi:10.7164/antibiotics.36.709. PMID 6874593. 
  5. ^ http://ainotes.wikispaces.com/file/view/PREPEN_Package_Insert.pdf