Bephenium hydroxynaphthoate

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Bephenium hydroxynaphthoate
Bephenium hydroxynaphthoate.svg
Clinical data
Pregnancy
category
  • Undefined
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Bioavailability <1%
Excretion Renal (negligible)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
Formula C28H29NO4
Molar mass 443.54 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Bephenium hydroxynaphthoate (INN, trade names Alcopara, Alcopar, Befenium, Debefenium, Francin, Nemex) is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.[1][2] It is formulated as a salt between the active pharmaceutical ingredient, bephenium, and 3-hydroxy-2-naphthoic acid.

Bephenium is not FDA-approved and is not available in the United States.[3]

References[edit]

  1. ^ Sweetman S, ed. (2009). Martindale: The complete drug reference (36th ed.). London: Pharmaceutical Press. p. 143. ISBN 978-0-85369-840-1. 
  2. ^ Jayewardene G, Ismail MM, Wijayaratnam Y (July 1960). "Bephenium hydroxynaphthoate in treatment of ascariasis". Br Med J. 2 (5194): 268–71. doi:10.1136/bmj.2.5194.268. PMC 2097409Freely accessible. PMID 14406934. 
  3. ^ Pham PA (March 19, 2009). "Bephenium hydroxynaphthoate". Point-of-Care Information Technology ABX Guide. Johns Hopkins University.  Retrieved on March 25, 2011.