Bereina is a town in the Central Province of Papua New Guinea. It is located on the Hiritano Highway about 160 kilometres (100 mi) north-west of Port Moresby, and contains the headquarters of both the Kairuku-Hiri District and the Kairuku Rural local-level government area. Bereina also hosts a regional airport.
Bereina is home to three elementary schools and one primary school. A short distance to the south is Mainohana Catholic High School, a De La Salle Year 9–12 school established in 1958.