Started as a small local grocery store in 1977, it now has two locations in Berkeley. The original store was located in a converted bowling alley (also named Berkeley Bowl) at 2777 Shattuck Avenue, and moved to a renovated Safeway at 2020 Oregon Street in 1999. In 2003, it employed 250 people and there was a drive for unionization. A second location, Berkeley Bowl West, opened at 9th and Heinz in 2009.
In 2008, the Los Angeles Times wrote that it was "this strident city's most popular grocery store."