The river rises from the Tadrida Scarp and flows in a north-easterly direction through the Drysdale River National Park and the Oombulgarri Indigenous Reserve before discharging into the Timor Sea. The river has two tributaries the De Lancourt River and Casuarina Creek.
The traditional owners of the areas around the river are the Miwa peoples. The river was names by the explorer Charles Price Conigrave in 1911 who was the first European to discover the river. He named the river after his brother Berkeley Fairfax Conigrave.
It is regularly visited by MV True North while on Kimberley coastal cruises.