Bernhard Palsson

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Bernhard Palsson
Born Bernhard Ørn Palsson
1957 (age 59–60)[1]
Alma mater University of Wisconsin–Madison (PhD)
Thesis Mathematical Modelling of Dynamics and Control in Metabolic Networks (1984)
Doctoral advisor Edwin N. Lightfoot[3]
Doctoral students
Notable awards

Bernhard Ørn Palsson is the Galletti Professor of Bioengineering and an Adjunct Professor of Medicine at the University of California, San Diego.[5][6][7]


Palsson received his PhD from the University of Wisconsin–Madison[8] in 1984 under the supervision of Edwin N. Lightfoot.[3]


Upon graduation Palsson joined the chemical engineering faculty at University of Michigan where he served as a professor until 1995. In 1995, he joined the department of Bioengineering at University of California, San Diego and was named the Galetti Chair of Bioengineering in 2004. He is also a Faculty member of Keio University.[9]

Palsson has authored or co-authored over 300 peer-reviewed scientific articles[10][11] and is the holder of over 35 patents.[5] His research interests include metabolic network modelling,[12] systems biology,[13][14][15] tissue engineering[16] and cell culture,[17] the development of analysis procedures for genome-scale models, and the experimental verification of these models in Escherichia coli,[18][19][20] Saccharomyces cerevisiae[21][22] and other important organisms.

Palsson serves on the editorial board of several scientific journals including Annals of Biomedical Engineering, Biotechnology and Bioengineering, Metabolic Engineering and Molecular Systems Biology. He was inducted as a member of the National Academy of Engineering in 2006 and a fellow of the American Association for the Advancement of Science in 2011.


  1. ^
  2. ^ "Archived copy". Archived from the original on 2010-12-20. Retrieved 2011-07-03.  Bernhard Palsson, Professor, Designated CEO Biosustain
  3. ^ a b Palsson, B. O.; Lightfoot, E. N. (1984). "Mathematical modelling of dynamics and control in metabolic networks. I. On Michaelis-Menten kinetics". Journal of Theoretical Biology. 111 (2): 273–302. PMID 6513572. doi:10.1016/S0022-5193(84)80211-8. 
  4. ^ Alumni of the Palsson laboratory
  5. ^ a b Bernhard Palsson at USCD
  6. ^ List of publications from Microsoft Academic Search
  7. ^ Bernhard Palsson's publications indexed by the Scopus bibliographic database, a service provided by Elsevier. (subscription required)
  8. ^
  9. ^ "Bernhard Palsson, Professor, Designated CEO". Biosustain. Retrieved 26 April 2013. 
  10. ^ Search Results for author Palsson BO on PubMed.
  11. ^ Bernhard Palsson in Google Scholar
  12. ^ Varma, A.; Palsson, B. O. (1994). "Metabolic Flux Balancing: Basic Concepts, Scientific and Practical Use". Bio/Technology. 12 (10): 994–998. doi:10.1038/nbt1094-994. 
  13. ^ Palsson, Bernhard (2006). Systems biology: properties of reconstructed networks. Cambridge, UK: Cambridge University Press. ISBN 0-521-85903-4. 
  14. ^ Palsson, Bernhard (2011). Systems Biology: Simulation of Dynamic Network States. Cambridge, UK: Cambridge University Press. ISBN 1-107-00159-5. 
  15. ^ Thiele, I.; Swainston, N.; Fleming, R. M. T.; Hoppe, A.; Sahoo, S.; Aurich, M. K.; Haraldsdottir, H.; Mo, M. L.; Rolfsson, O.; Stobbe, M. D.; Thorleifsson, S. G.; Agren, R.; Bölling, C.; Bordel, S.; Chavali, A. K.; Dobson, P.; Dunn, W. B.; Endler, L.; Hala, D.; Hucka, M.; Hull, D.; Jameson, D.; Jamshidi, N.; Jonsson, J. J.; Juty, N.; Keating, S.; Nookaew, I.; Le Novère, N.; Malys, N.; Mazein, A. (2013). "A community-driven global reconstruction of human metabolism". Nature Biotechnology. 31 (5): 419–425. PMC 3856361Freely accessible. PMID 23455439. doi:10.1038/nbt.2488. 
  16. ^ Bhatia, Sangeeta; Palsson, Bernhard (2004). Tissue engineering. Upper Saddle River, NJ: Pearson Prentice Hall. ISBN 0-13-041696-7. 
  17. ^ Palsson, Bernhard; Masters, John C. (1999). Cancer cell lines. Boston: Kluwer Academic Publishers. ISBN 0-7923-5878-3. 
  18. ^ Covert, M. W.; Knight, E. M.; Reed, J. L.; Herrgard, M. J.; Palsson, B. O. (2004). "Integrating high-throughput and computational data elucidates bacterial networks". Nature. 429 (6987): 92–96. PMID 15129285. doi:10.1038/nature02456. 
  19. ^ Reed, J. L.; Vo, T. D.; Schilling, C. H.; Palsson, B. O. (2003). "An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)". Genome Biology. 4 (9): R54. PMC 193654Freely accessible. PMID 12952533. doi:10.1186/gb-2003-4-9-r54. 
  20. ^ Edwards, J. S.; Ibarra, R. U.; Palsson, B. O. (2001). "In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data". Nature Biotechnology. 19 (2): 125–130. PMID 11175725. doi:10.1038/84379. 
  21. ^ Forster, J.; Famili, I.; Fu, P.; Palsson, B. Ø.; Nielsen, J. (2003). "Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network". Genome Research. 13 (2): 244–253. PMC 420374Freely accessible. PMID 12566402. doi:10.1101/gr.234503. 
  22. ^ Herrgård, M. J.; Swainston, N.; Dobson, P.; Dunn, W. B.; Arga, K. Y. I.; Arvas, M.; Blüthgen, N.; Borger, S.; Costenoble, R.; Heinemann, M.; Hucka, M.; Le Novère, N.; Li, P.; Liebermeister, W.; Mo, M. L.; Oliveira, A. P.; Petranovic, D.; Pettifer, S.; Simeonidis, E.; Smallbone, K.; Spasić, I.; Weichart, D.; Brent, R.; Broomhead, D. S.; Westerhoff, H. V.; Kirdar, B. L.; Penttilä, M.; Klipp, E.; Palsson, B. Ø.; Sauer, U.; Oliver, S.G.; Mendes, P.; Nielsen, J.; Kell, D.B. (2008). "A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology". Nature Biotechnology. 26 (10): 1155–1160. PMC 4018421Freely accessible. PMID 18846089. doi:10.1038/nbt1492.