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Β-Fuoxymorphamine

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beta-Fuoxymorphamine
Names
IUPAC name
Methyl (2E)-4-{[(5α,6β)-3,14-dihydroxy-17-methyl-4,5-epoxymorphinan-6-yl]amino}-4-oxo-2-butenoate
Identifiers
3D model (JSmol)
Abbreviations β-FOA
ChemSpider
  • InChI=1S/C22H26N2O6/c1-24-10-9-21-18-12-3-4-14(25)19(18)30-20(21)13(7-8-22(21,28)15(24)11-12)23-16(26)5-6-17(27)29-2/h3-6,13,15,20,25,28H,7-11H2,1-2H3,(H,23,26)/b6-5+/t13-,15-,20+,21+,22-/m1/s1
    Key: VYGVQURMYFVOPO-IRYZUVSXSA-N
  • O=C(OC)\C=C\C(=O)N[C@H]4[C@@H]5Oc1c2c(ccc1O)C[C@H]3N(CC[C@]25[C@@]3(O)CC4)C
Properties
C22H26N2O6
Molar mass 414.458 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

beta-Fuoxymorphamine (β-fuoxymorphamine) is an opioid acting at μ-opioid receptors. It is used experimentally.[1]

See also

References

  1. ^ Huang, Weijiao; Manglik, Aashish; Venkatakrishnan, A. J.; Laeremans, Toon; Feinberg, Evan N.; Sanborn, Adrian L.; Kato, Hideaki E.; Livingston, Kathryn E.; Thorsen, Thor S.; Kling, Ralf C.; Granier, Sébastien; Gmeiner, Peter; Husbands, Stephen M.; Traynor, John R.; Weis, William I.; Steyaert, Jan; Dror, Ron O.; Kobilka, Brian K. (2015). "Structural insights into µ-opioid receptor activation". Nature. 524 (7565): 315–321. doi:10.1038/nature14886.