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Tietjen studied German studies, art history and Romance studies at University of Münster and in Paris. After university studies she worked as journalist at RIAS and then at NDR. From January 1997 to September 2007 she was together with Eva Hermann talk show host of Stargeflüster' on NDR: Together with Eckart von Hirschhausen she is since September 2009 talk show host of Tietjen und Hirschhausen on German broadcaster Norddeutscher Rundfunk.