Scardovi and Trovatelli 1974
B. a. animalis
Bifidobacterium animalis and Bifidobacterium lactis were previously described as two distinct species. Presently, both are considered B. animalis with the subspecies Bifidobacterium animalis subsp. animalis and Bifidobacterium animalis subsp. lactis.
Both old names B. animalis and B. lactis are still used on product labels, as this species is frequently used as a probiotic. In most cases, which subspecies is used in the product is not clear.
Several companies have attempted to trademark particular strains, and as a marketing technique, have invented scientific-sounding names for the strains.
Danone (Dannon) markets the subspecies strain DN 173 010 as Bifidus Digestivum (UK), Bifidus Regularis (US and Mexico), Bifidobacterium Lactis or B.L. Regularis (Canada), DanRegularis (Brazil), Bifidus Actiregularis (Argentina, Austria, Belgium, Bulgaria, Chile, Czech Republic, France, Germany, Greece, Hungary, Israel, Italy, Kazakhstan, Netherlands, Portugal, Romania, Russia, South Africa, Spain and the UK), and Bifidus Essensis in the Middle East (and formerly in Hungary, Bulgaria and The Netherlands) through Activia from Safi Danone KSA.
Lidl lists "Bifidobacterium BB-12" in its "Proviact" yogurt.
Bifidobacterim animalis subspecies lactis BB-12 administered in combination with other probiotics has showed a small beneficial effect in a study of 32 patients with ulcerative colitis.
The manipulation of the gut flora is complex and may cause bacteria-host interactions. Although probiotics, in general, are considered safe, there are concerns about their use in certain cases. Some people, such as those with compromised immune systems, short bowel syndrome, central venous catheters, heart valve disease and premature infants, may be at higher risk for adverse events. Rarely, consumption of probiotics may cause bacteremia, and sepsis, potentially fatal infections in children with lowered immune systems or who are already critically ill.
- Masco, Liesbeth; Marco Ventura; Ralf Zink; Geert Huys; Jean Swings (July 2004). "Polyphasic taxonomic analysis of Bifidobacterium animalis and Bifidobacterium lactis reveals relatedness at the subspecies level: reclassification of Bifidobacterium animalis as Bifidobacterium animalis subsp. animalis subsp. nov. and Bifidobacterium lactis as Bifidobacterium animalis subsp. lactis subsp. nov.". Int J Syst Evol Microbiol. 54 (part 4): 1137–1143. doi:10.1099/ijs.0.03011-0. PMID 15280282. Retrieved 2007-07-14.
- Rapid Identification, Differentiation, and Proposed New Taxonomic Classification of Bifidobacterium lactis. Appl Environ Microbiol. 2002 December; 68(12): 6429–6434.
- Ghouri YA, Richards DM, Rahimi EF, Krill JT, Jelinek KA, DuPont AW (Dec 9, 2014). "Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease". Clin Exp Gastroenterol (Review). 7: 473–87. doi:10.2147/CEG.S27530. PMC . PMID 25525379.
- "American Society for MicrobiologyApplied and Environmental Microbiology." Strain-Specific Genotyping of Bifidobacterium Animalis Subsp. Lactis by Using Single-Nucleotide Polymorphisms, Insertions, and Deletions. N.p., n.d. Web. 03 June 2014.
- Durchschein F, Petritsch W, Hammer HF (2016). "Diet therapy for inflammatory bowel diseases: The established and the new.". World J Gastroenterol (Review). 22 (7): 2179–94. doi:10.3748/wjg.v22.i7.2179. PMC . PMID 26900283.
- Boyle RJ, Robins-Browne RM, Tang ML (2006). "Probiotic use in clinical practice: what are the risks?". Am J Clin Nutr (Review). 83 (6): 1256–64; quiz 1446–7. PMID 16762934.
- Doron S, Snydman DR (2015). "Risk and safety of probiotics.". Clin Infect Dis (Review). 60 Suppl 2: S129–34. doi:10.1093/cid/civ085. PMC . PMID 25922398.
- Singhi SC, Kumar S (2016). "Probiotics in critically ill children.". F1000Res (Review). 5. doi:10.12688/f1000research.7630.1. PMC . PMID 27081478.
- whatisbifidusregularis.org/ – A deconstruction of the terms Bifidus Actiregularis, Bifidus Regularis, Bifidus Digestivum, L. Casei Immunitas and their variants, as well as the marketing strategy, and information about the potential health benefits of live yoghurts.
- Food-Info.net – How to select a probiotic
- Type strain of Bifidobacterium animalis at BacDive - the Bacterial Diversity Metadatabase