Biliverdin reductase A

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biliverdin reductase A
Bilivra.jpg
Biliverdin reductase A dimer, Human
Identifiers
EC number 1.3.1.24
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
BLVRA
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesBLVRA, BLVR, BVR, BVRA, biliverdin reductase A
External IDsMGI: 88170 HomoloGene: 572 GeneCards: BLVRA
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for BLVRA
Genomic location for BLVRA
Band7p13Start43,758,680 bp[1]
End43,807,342 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000712
NM_001253823

NM_026678

RefSeq (protein)

NP_000703
NP_001240752

NP_080954

Location (UCSC)Chr 7: 43.76 – 43.81 MbChr 2: 127.07 – 127.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Biliverdin reductase A is a protein that in humans is encoded by the BLVRA gene.[5]

Function[edit]

The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH.[5]

Clinical significance[edit]

Mutations in this gene are associated with hyperbiliverdinemia.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106605 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001999 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b c "Entrez Gene: Biliverdin reductase A".

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.