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Biological clock may refer to:
- Age and female fertility, decrease of female fertility with advancing maternal age
- Ageing, biological programme that limits the lifespan of an individual
- Circadian clock, a molecular mechanism that results in a circadian rhythm in a living organism
- Circadian rhythm, biological process that displays an oscillation of about 24 hours, such as the human sleep-wake cycle (the "body clock")
- Epigenetic clock, a set of DNA sites whose methylation levels can be used to measure aging throughout the body
- Molecular clock a technique that uses the mutation rate of a biomolecule to deduce the time in prehistory when two life forms diverged
- Vernalisation the induction of flowering by prolonged exposure to low temperatures, as during the winter in a temperate climate
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