From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Blast2GO Logo.png
TypeBioinformatics Software
Inception2011 (2011)
ManufacturerBioBam Bioinformatics
Models madeDemo, Basic, Trial, Pro, Plugin, Commandline

Blast2GO, first published in 2005,[1][2][3][4] is a bioinformatics software tool for the automatic, high-throughput functional annotation of novel sequence data (genes proteins). It makes use of the BLAST[5] algorithm to identify similar sequences to then transfers existing functional annotation from yet characterised sequences to the novel one. The functional information is represented via the Gene Ontology (GO), a controlled vocabulary of functional attributes. The Gene Ontology, or GO, is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species.[6]

See also[edit]


  1. ^ Conesa, A; Götz, S; García-Gómez, JM; Terol, J; Talón, M; Robles, M (Sep 15, 2005). "Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research". Bioinformatics. 21 (18): 3674–6. doi:10.1093/bioinformatics/bti610. PMID 16081474.
  2. ^ Götz, S; García-Gómez, JM; Terol, J; Williams, TD; Nagaraj, SH; Nueda, MJ; Robles, M; Talón, M; Dopazo, J; Conesa, A (June 2008). "High-throughput functional annotation and data mining with the Blast2GO suite". Nucleic Acids Research. 36 (10): 3420–35. doi:10.1093/nar/gkn176. PMC 2425479. PMID 18445632.
  3. ^ Conesa, A; Götz, S (2008). "Blast2GO: A comprehensive suite for functional analysis in plant genomics". International Journal of Plant Genomics. 2008: 1–12. doi:10.1155/2008/619832. PMC 2375974. PMID 18483572.
  4. ^ Götz, S; Arnold, R; Sebastián-León, P; Martín-Rodríguez, S; Tischler, P; Jehl, MA; Dopazo, J; Rattei, T; Conesa, A (Apr 1, 2011). "B2G-FAR, a species-centered GO annotation repository". Bioinformatics. 27 (7): 919–24. doi:10.1093/bioinformatics/btr059. PMC 3065692. PMID 21335611.
  5. ^ Altschul, SF; Gish, W; Miller, W; Myers, EW; Lipman, DJ (Oct 5, 1990). "Basic local alignment search tool". Journal of Molecular Biology. 215 (3): 403–10. doi:10.1016/S0022-2836(05)80360-2. PMID 2231712.
  6. ^ The Gene Ontology Consortium (January 2008). "The Gene Ontology project in 2008". Nucleic Acids Res. 36 (Database issue): D440–4. doi:10.1093/nar/gkm883. PMC 2238979. PMID 17984083.

External links[edit]

  • Official website Blast2GO - Tool for functional annotation of (novel) sequences and the analysis of annotation data.
  • Company developing Blast2GO — BioBam Bioinformatics S.L., a bioinformatics company dedicated to creating user-friendly software for the scientific community is developing, maintaining and distributing Blast2GO.
  • Gene Ontology Tools — Provides access to the ontologies, software tools, annotated gene product lists, and reference documents describing the GO and its uses.
  • PlantRegMap—Plant GO annotation for 165 species and GO enrichment analysis