Blue Monday may refer to:
- Blue Monday (term), workers hungover from a weekend's drinking
- Blue Monday (comics), a comic book by Chynna Clugston-Major
- Blue Monday (date), supposedly the most depressing day of the year
- "Blue Monday" (Eureka Seven episode), the pilot episode of the anime series Eureka Seven
- The last game of the 1981 National League Championship Series between the Montreal Expos and the Los Angeles Dodgers
- "Blue Monday" (Fats Domino song), a 1950s song first recorded by Smiley Lewis and popularized by Fats Domino
- "Blue Monday" (New Order song), a 1983 song by New Order and covered by Orgy and Flunk
- Blue Monday (Flunk album), a 2002 album by Flunk
- "Blue Monday" (White Lion song), a 1991 instrumental by White Lion guitarist Vito Bratta
- Blue Monday (opera), the original name of a George Gershwin one-act "jazz opera"
- Blue Monday (band), a Vancouver hardcore punk band
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