London created his underground newspaper comic stripMerton, in his native New York in 1969 and the raunchy Dirty Duck strip in 1971. Dirty Duck had been originally published by the Los Angeles Free Press and subsequently in books like Air Pirates Funnies, and The Fabulous Furry Freak Brothers. His non-duck work also appeared in underground titles such as Merton of the Movement, Left Field Funnies, Douglas Comics, Facts O' Life Funnies and El Perfecto Comics. In 1972 London moved Dirty Duck to the original National Lampoon where it was a regular monthly feature until 1976; it continued to run in Playboy for over 25 years.
In 1975, a film entitled Down and Dirty Duck was released. While promoted under the abbreviated title Dirty Duck, the film itself is not related to London's character or comics.