Bone morphogenetic protein 3

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Not to be confused with BMP-3.
BMP3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases BMP3, BMP-3A, bone morphogenetic protein 3
External IDs OMIM: 112263 MGI: 88179 HomoloGene: 927 GeneCards: 651
RNA expression pattern
PBB GE BMP3 208244 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001201

NM_173404
NM_001310677

RefSeq (protein)

NP_001192.2

NP_775580.1

Location (UCSC) Chr 4: 81.03 – 81.06 Mb Chr 5: 98.85 – 98.88 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Bone morphogenetic protein 3, also known as osteogenin, is a protein in humans that is encoded by the BMP3 gene.[1]

The protein encoded by this gene is a member of the transforming growth factor beta superfamily. It, like other bone morphogenetic proteins (BMP's) is known for its ability to induce bone and cartilage development. It is a disulfide-linked homodimer. It negatively regulates bone density. BMP3 is an antagonist to other BMP's in the differentiation of osteogenic progenitors.

It is highly expressed in fractured tissues.

References[edit]

Further reading[edit]