Boothby may refer to:
- Boothby (surname)
- Boothby Graffoe (comedian) (born James Martyn Rogers in 1962), English comedian, singer, songwriter and playwright
- Boothby baronets, two titles in the Baronetage of England, one extant
- Boothby monument in St Oswald's Church, Ashbourne, England
- Boothby (Star Trek), groundskeeper at Starfleet Academy
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