3D model (JSmol)
|E number||E284 (preservatives)|
CompTox Dashboard (EPA)
|Molar mass||61.83 g·mol−1|
|Appearance||White crystalline solid|
|Melting point||170.9 °C (339.6 °F; 444.0 K)|
|Boiling point||300 °C (572 °F; 573 K)|
|2.52 g/100 mL (0 °C) |
4.72 g/100 mL (20 °C)
5.7 g/100 mL (25 °C)
19.10 g/100 mL (80 °C)
27.53 g/100 mL (100 °C)
|Solubility in other solvents||Soluble in lower alcohols |
moderately soluble in pyridine
very slightly soluble in acetone
|Acidity (pKa)||9.24, 12.4, 13.3|
|S02AA03 (WHO) D08AD (WHO)|
|Safety data sheet||See: data page|
|NFPA 704 (fire diamond)|
|Lethal dose or concentration (LD, LC):|
LD50 (median dose)
|2660 mg/kg, oral (rat)|
|Supplementary data page|
|Refractive index (n),|
Dielectric constant (εr), etc.
|UV, IR, NMR, MS|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Boric acid, also called hydrogen borate, boracic acid, and orthoboric acid is a weak, monobasic Lewis acid of boron. However, some of its behaviour towards some chemical reactions suggest it to be tribasic acid in Bronsted sense as well. Boric acid is often used as an antiseptic, insecticide, flame retardant, neutron absorber, or precursor to other chemical compounds. It has the chemical formula H3BO3 (sometimes written B(OH)3), and exists in the form of colorless crystals or a white powder that dissolves in water. When occurring as a mineral, it is called sassolite.
Boric acid, or sassolite, is found mainly in its free state in some volcanic districts, for example, in the Italian region of Tuscany, the Lipari Islands and the US state of Nevada. In these volcanic settings it issues, mixed with steam, from fissures in the ground. It is also found as a constituent of many naturally occurring minerals – borax, boracite, ulexite (boronatrocalcite) and colemanite. Boric acid and its salts are found in seawater. It is also found in plants, including almost all fruits.
Boric acid was first prepared by Wilhelm Homberg (1652–1715) from borax, by the action of mineral acids, and was given the name sal sedativum Hombergi ("sedative salt of Homberg"). However borates, including boric acid, have been used since the time of the ancient Greeks for cleaning, preserving food, and other activities.
- Na2B4O7·10H2O + 2 HCl → 4 B(OH)3 [or H3BO3] + 2 NaCl + 5 H2O
- B2H6 + 6 H2O → 2 B(OH)3 + 6 H2
- BX3 + 3 H2O → B(OH)3 + 3 HX (X = Cl, Br, I)
Boric acid is soluble in boiling water. When heated above 170 °C, it dehydrates, forming metaboric acid (HBO2):
- H3BO3 → HBO2 + H
Metaboric acid is a white, cubic crystalline solid and is only slightly soluble in water. Metaboric acid melts at about 236 °C, and when heated above about 300 °C further dehydrates, forming tetraboric acid, also called pyroboric acid (H2B4O7):
- 4 HBO2 → H2B4O7 + H
- H2B4O7 → 2 B2O3 + H
There are conflicting interpretations for the origin of the acidity of aqueous boric acid solutions. Raman spectroscopy of strongly alkaline solutions has shown the presence of B(OH)−
4 ion, leading some to conclude that the acidity is exclusively due to the abstraction of OH− from water:
or more properly expressed in the aqueous solution:
- B(OH)3 + 2 H
2O ⇌ B(OH)−
4 + H
Boric acid makes an important contribution to the absorption of low frequency sound in seawater.
With polyols containing cis-vicinal diols, such as glycerol and mannitol, the acidity of the boric acid solution is increased. With different mannitol concentrations, the pK of B(OH)3 extends on five orders of magnitude (from 9 to 4): this exacerbed acidity of boric acid in the presence of mannitol is also sometimes referred as "mannitoboric acid". Greenwood and Earnshawn (1997) refer to a pK value of 5.15 while a pK value of 3.80 is also reported in Vogel's book. This is due to the formation of a boron-mannitol chelate, [B(C6H8O2(OH)4)2]−, also known as mannitoborate complex, according to the following complexation reaction releasing a proton:
- ⇌ + 3 H2O + H+
- (pKa ranging from 4 to 9, depending on the mannitol concentration)
This feature is used in analytical chemistry to determine the boron content in aqueous solution by potentiometric titration with a strong base, such as NaOH.
Boric acid also dissolves in anhydrous sulfuric acid:
- B(OH)3 + 6 H2SO4 → B(HSO4)4− + 2 HSO4− + 3 H3O+
- B(OH)3 + 3 ROH → B(OR)3 + 3 H2O
A variety of salts are also known, involving the planar trigonal BO33– borate anion.
Molecular and crystal structure
Crystalline boric acid consists of layers of B(OH)3 molecules held together by hydrogen bonds of length 272 pm. The distance between two adjacent layers is 318 pm.
allows boric acid molecules to form
parallel layers in the solid state
Based on mammalian median lethal dose (LD50) rating of 2,660 mg/kg body mass, boric acid is only poisonous if taken internally or inhaled in large quantities. The Fourteenth Edition of the Merck Index indicates that the LD50 of boric acid is 5.14 g/kg for oral dosages given to rats, and that 5 to 20 g/kg has produced death in adult humans. For comparison's sake, the LD50 of salt is reported to be 3.75 g/kg in rats according to the Merck Index. According to the Agency for Toxic Substances and Disease Registry, "The minimal lethal dose of ingested boron (as boric acid) was reported to be 2–3 g in infants, 5–6 g in children, and 15–20 g in adults. [...] However, a review of 784 human poisonings with boric acid (10–88 g) reported no fatalities, with 88% of cases being asymptomatic."
Long-term exposure to boric acid may be of more concern, causing kidney damage and eventually kidney failure (see links below). Although it does not appear to be carcinogenic, studies in dogs have reported testicular atrophy after exposure to 32 mg/kg bw/day for 90 days. This level is far lower than the LD50.
According to the CLH report for boric acid published by the Bureau for Chemical Substances Lodz, Poland, boric acid in high doses shows significant developmental toxicity and teratogenicity in rabbit, rat, and mouse fetuses as well as cardiovascular defects, skeletal variations, and mild kidney lesions. As a consequence in the 30th ATP to EU directive 67/548/EEC of August 2008, the European Commission decided to amend its classification as reprotoxic category 2, and to apply the risk phrases R60 (may impair fertility) and R61 (may cause harm to the unborn child).
At a 2010 European Diagnostics Manufacturing Association (EDMA) Meeting, several new additions to the Substance of Very High Concern (SVHC) candidate list in relation to the Registration, Evaluation, Authorisation and Restriction of Chemicals Regulations 2007 (REACH) were discussed. Following the registration and review completed as part of REACH, the classification of Boric Acid CAS 10043-35-3 / 11113-50-1 is listed from 1 December 2010 is H360FD (May damage fertility. May damage the unborn child.)
The primary industrial use of boric acid is in the manufacture of monofilament fiberglass usually referred to as textile fiberglass. Textile fiberglass is used to reinforce plastics in applications that range from boats, to industrial piping to computer circuit boards.
In electroplating, boric acid is used as part of some proprietary formulas. One such known formula calls for about a 1 to 10 ratio of H
3 to NiSO
4, a very small portion of sodium lauryl sulfate and a small portion of H
Boric acid, mixed with borax (sodium tetraborate decahydrate) at the weight ratio of 4:5, is highly soluble in water, though they are not so soluble separately. The solution is used for fire retarding agent of wood by impregnation.
Boric acid is one of the most commonly used substances that can counteract the harmful effects of reactive hydrofluoric acid (HF) after an accidental contact with the skin. It works by forcing the free F− anions into complex salts. This process defeats the extreme toxicity of hydrofluoric acid, particularly its ability to sequester ionic calcium from blood serum which can lead to cardiac arrest and bone decomposition; such an event can occur from just minor skin contact with HF.
Boric acid is also present in the list of chemical additives used for hydraulic fracturing (fracking) in the Marcellus Shale in Pennsylvania. Indeed, it is often used in conjonction with guar gum as cross-linking and gelling agent for controlling the viscosity and the rheology of the fracking fluid injected at high pressure in the well. Indeed, it is important to control the fluid viscosity for keeping in suspension on long transport distances the grains of the propping agents aimed at maintaining the cracks in the shales sufficiently open to facilitate the gas extraction after the hydraulic pressure is relieved. The rheological properties of borate cross-linked guar gum hydrogel mainly depend on the pH value.
Boric acid can be used as an antiseptic for minor burns or cuts and is sometimes used in salves and dressings, such as boracic lint. Boric acid is applied in a very dilute solution as an eye wash. Dilute boric acid can be used as a vaginal douche to treat bacterial vaginosis due to excessive alkalinity, as well as candidiasis due to non-albicans candida. As an antibacterial compound, boric acid can also be used as an acne treatment. It is also used as prevention of athlete's foot, by inserting powder in the socks or stockings. Various preparations can be used to treat some kinds of otitis externa (ear infection) in both humans and animals. The preservative in urine sample bottles in the UK is boric acid.
Boric acid solutions used as an eye wash or on abraded skin are known to be toxic, particularly to infants, especially after repeated use; this is because of its slow elimination rate.
Boric acid was first registered in the US as an insecticide in 1948 for control of cockroaches, termites, fire ants, fleas, silverfish, and many other insects. The product is generally considered to be safe to use in household kitchens to control cockroaches and ants. It acts as a stomach poison affecting the insects' metabolism, and the dry powder is abrasive to the insects' exoskeletons. Boric acid also has the reputation as "the gift that keeps on killing" in that cockroaches that cross over lightly dusted areas do not die immediately, but that the effect is like shards of glass cutting them apart. This often allows a roach to go back to the nest where it soon dies. Cockroaches, being cannibalistic, eat others killed by contact or consumption of boric acid, consuming the powder trapped in the dead roach and killing them, too.
In combination with its use as an insecticide, boric acid also prevents and destroys existing wet and dry rot in timbers. It can be used in combination with an ethylene glycol carrier to treat external wood against fungal and insect attack. It is possible to buy borate-impregnated rods for insertion into wood via drill holes where dampness and moisture is known to collect and sit. It is available in a gel form and injectable paste form for treating rot affected wood without the need to replace the timber. Concentrates of borate-based treatments can be used to prevent slime, mycelium, and algae growth, even in marine environments.
Boric acid in equilibrium with its conjugate base the borate ion is widely used (in the concentration range 50 - 100 ppm boron equivalents) as a primary or adjunct pH buffer system in swimming pools. Boric acid is a weak acid, with pKa (the pH at which buffering is strongest because the free acid and borate ion are in equal concentrations) of 9.24 in pure water at 25 °C. But apparent pKa is substantially lower in swimming pool or ocean waters because of interactions with various other molecules in solution. It will be around 9.0 in a salt-water pool. No matter which form of soluble boron is added, within the acceptable range of pH and boron concentration for swimming pools, boric acid is the predominant form in aqueous solution, as shown in the accompanying figure. The boric acid - borate system can be useful as a primary buffer system (substituting for the bicarbonate system with pKa1 = 6.0 and pKa2 = 9.4 under typical salt-water pool conditions) in pools with salt-water chlorine generators that tend to show upward drift in pH from a working range of pH 7.5 - 8.2. Buffer capacity is greater against rising pH (towards the pKa around 9.0), as illustrated in the accompanying graph. The use of boric acid in this concentration range does not allow any reduction in free HOCl concentration needed for pool sanitation, but it may add marginally to the photo-protective effects of cyanuric acid and confer other benefits through anti-corrosive activity or perceived water softness, depending on overall pool solute composition.
Colloidal suspensions of nanoparticles of boric acid dissolved in petroleum or vegetable oil can form a remarkable lubricant on ceramic or metal surfaces with a coefficient of sliding friction that decreases with increasing pressure to a value ranging from 0.10 to 0.02. Self-lubricating H3BO3 films result from a spontaneous chemical reaction between water molecules and B2O3 coatings in a humid environment. In bulk-scale, an inverse relationship exists between friction coefficient and Hertzian contact pressure induced by applied load.
Boric acid is used in some nuclear power plants as a neutron poison. The boron in boric acid reduces the probability of thermal fission by absorbing some thermal neutrons. Fission chain reactions are generally driven by the probability that free neutrons will result in fission and is determined by the material and geometric properties of the reactor. Natural boron consists of approximately 20% boron-10 and 80% boron-11 isotopes. Boron-10 has a high cross-section for absorption of low energy (thermal) neutrons. By increasing boric acid concentration in the reactor coolant, the probability that a neutron will cause fission is reduced. Changes in boric acid concentration can effectively regulate the rate of fission taking place in the reactor. Boric acid is used only in pressurized water reactors (PWRs) whereas boiling water reactors (BWRs) employ control rod pattern and coolant flow for power control. BWRs use an aqueous solution of boric acid and borax or sodium pentaborate for an emergency shut down system. Boric acid may be dissolved in spent fuel pools used to store spent fuel elements. The concentration is high enough to keep neutron multiplication at a minimum. Boric acid was dumped over Reactor 4 of the Chernobyl nuclear power plant after its meltdown to prevent another reaction from occurring.
Boron is used in pyrotechnics to prevent the amide-forming reaction between aluminum and nitrates. A small amount of boric acid is added to the composition to neutralize alkaline amides that can react with the aluminum.
Boric acid can be used as a colorant to make fire green. For example, when dissolved in methanol it is popularly used by fire jugglers and fire spinners to create a deep green flame much stronger than copper sulfate.
- Allen, A. H.; Tankard, A. R. (1904). "The Determination of Boric Acid in Cider, Fruits, etc". Analyst. 29 (October): 301–304. Bibcode:1904Ana....29..301A. doi:10.1039/an9042900301.
- Ronald Eisler (2007). Eisler's Encyclopedia of Environmentally Hazardous Priority Chemicals. Elsevier. p. 59. ISBN 9780080547077.
- Housecroft, C. E.; Sharpe, A. G. (2008). "Chapter 13: The Group 13 Elements". Inorganic Chemistry (3rd ed.). Pearson. p. 340. ISBN 978-0-13-175553-6.
- Balci, Suna; Sezgi, Naime; Eren, Esin (2012). "Boron Oxide Production Kinetics Using Boric Acid as Raw Material". Industrial & Engineering Chemistry Research. 51 (34): 11091–11096. doi:10.1021/ie300685x.
- Jolly, W. L. (1984). Modern Inorganic Chemistry. McGraw-Hill. p. 198.
- Housecroft, C.E.; Sharpe, A.G. (2005). Inorganic Chemistry (2nd ed.). Pearson Prentice-Hall. pp. 314–5.
- MHE. Comprehensive Chemistry for JEE Advanced 2014. Tata McGraw-Hill Education. p. 15.5. ISBN 9781259064265 – via Google Books.
- Darpan, Pratiyogita (1 May 2000). Competition Science Vision. Pratiyogita Darpan – via Internet Archive.
- "Underlying Physics and Mechanisms for the Absorption of Sound in Seawater". National Physical Laboratory. Retrieved 21 April 2008.
- NIST Special Publication. U.S. Government Printing Office. 1969.
- Greenwood, Norman N.; Earnshaw, Alan (1997). Chemistry of the Elements (2nd ed.). Butterworth-Heinemann. ISBN 978-0-08-037941-8.
- Mendham, J.; Denney, R. C.; Barnes, J. D.; Thomas, M. J. K. (2000), Vogel's Quantitative Chemical Analysis (6th ed.), New York: Prentice Hall, p. 357, ISBN 0-582-22628-7
- Brown, Herbert C.; Mead, Edward J.; Shoaf, Charles J. (1956). "Convenient procedures for the preparation of alkyl borate esters". J. Am. Chem. Soc. 78 (15): 3613–3614. doi:10.1021/ja01596a015.
- HHS, Public Health Service, Agency for Toxic Substances and Disease Registry (November 2010), Toxicological Profile for Boron (PDF), p. 11CS1 maint: uses authors parameter (link)
- Office of Prevention, Pesticides and Toxic Substances (2006). "Report of the Food Quality Protection Act (FQPA) Tolerance Reassessment Eligibility Decision (TRED) for Boric Acid/Sodium Borate Salts" (PDF). United States Environmental Protection Agency. Archived from the original (PDF) on 6 October 2006. Retrieved 21 April 2008. Cite journal requires
|journal=(help)CS1 maint: uses authors parameter (link)
- "CLH report for boric acid - Proposal for Harmonised Classification and Labelling" (PDF). Lodz, Poland: Bureau for Chemical Substances. 23 April 2018. Retrieved 18 October 2018.
- "Boric acid, ACC# 03260 MSDS" (PDF). 11 February 2008. Archived from the original (PDF) on 16 December 2011. Retrieved 24 September 2009.
- Ishii, Y.; Fujizuka, N.; Takahashi, T.; et al. (1993). "A fatal case of acute boric acid poisoning". Clinical Toxicology. 31 (2): 345–352. doi:10.3109/15563659309000402. PMID 8492348.
- Restuccio, A.; Mortensen, M. E.; Kelley, M. T. (1992). "Fatal ingestion of boric acid in an adult". American Journal of Emergency Medicine. 10 (6): 545–547. doi:10.1016/0735-6757(92)90180-6. PMID 1388380.
- Duldner, J. E. (30 January 2009). "Boric acid poisoning". A.D.A.M. Medical Encyclopedia. MedLine Plus.
- NSW Food Authority. "Borax and boric acid". Australia: New South Wales Government. Retrieved 24 September 2009.
- "Boric acid as a substance of very high concern because of its CMR properties" (PDF). ECHA Document library.
- Regulation (EC) No 1272/2008 of the European Parliament and of the Council, 16 December 2008
- Kistler, R. B.; Helvaci, C. (1994). "Boron and Borates". In Carr, D. D. (ed.). Industrial Minerals and Rocks (6th ed.). Littleton, CO: SME. pp. 171–186.
- Tsuyumoto, I.; Oshio, T.; Katayama, K. (2007). "Preparation of highly concentrated aqueous solution of sodium borate". Inorganic Chemistry Communications. 10 (1): 20–22. doi:10.1016/j.inoche.2006.08.019.
- Tsuyumoto, I.; Oshio, T. (2009). "Development of fire resistant laminated wood using concentrated sodium polyborate aqueous solution". Journal of Wood Chemistry and Technology. 29 (4): 277–285. doi:10.1080/02773810903033721.
- "Method 3052 microwave assisted acid digestion of siliceous and organically based matrices" (PDF). US EPA. 22 June 2015.
- Dempsey, Jock (2009) . "Borax". Dempsey's Forge. Retrieved 23 July 2010.
- Prager, Felice. "Science Becomes a Toy – Silly Putty". Loti.com. Rewind the Fifites. Archived from the original on 12 May 2013. Retrieved 7 June 2013.
- "Chemicals used by hydraulic fracturing companies in pennsylvania for surface and hydraulic fracturing activities" (PDF). Pennsylvania Department of Environmental Protection, Bureau of Oil and Gas Management. 30 June 2010.
- Fink, Johannes (2015). "Fracturing fluids". Petroleum Engineer's Guide to Oil Field Chemicals and Fluids. pp. 567–651. doi:10.1016/B978-0-12-803734-8.00017-5. ISBN 9780128037348.
- Bishop, Maximilienne; Shahid, Naureen; Yang, Jianzhong; Barron, Andrew R. (2004). "Determination of the mode and efficacy of the cross-linking of guar by borate using MAS11B NMR of borate cross-linked guar in combination with solution11B NMR of model systems". Dalton Trans. (17): 2621–2634. doi:10.1039/B406952H. ISSN 1477-9226. PMID 15514744.
- "European Patent EP3004279A1. Concentrated borate crosslinking solutions for use in hydraulic fracturing operations". European Patent Office. Retrieved 27 October 2019.
- Wang, Shibin; Tang, Hongbiao; Guo, Jianchun; Wang, Kunjie (2016). "Effect of pH on the rheological properties of borate crosslinked hydroxypropyl guar gum hydrogel and hydroxypropyl guar gum". Carbohydrate Polymers. 147: 455–463. doi:10.1016/j.carbpol.2016.04.029. ISSN 0144-8617. PMID 27178952.
- Abercrombie, P. (2010). "Vaginitis". In Maizes, V.; Low Dog, T. (eds.). Integrative Women's Health. New York, NY: Oxford University Press. p. 192. ISBN 978-0-19-537881-8.
- Iavazzo C, Gkegkes ID, Zarkada IM, Falagas ME (August 2011). "Boric acid for recurrent vulvovaginal candidiasis: the clinical evidence". J Womens Health (Larchmt). 20 (8): 1245–55. doi:10.1089/jwh.2010.2708. PMID 21774671.
- Adriztina, I.; Adenin, L. I.; Lubis, Y. M. (January 2018). "Efficacy of Boric Acid as a Treatment of Choice for Chronic Suppurative Otitis Media and Its Ototoxicity". Korean J Fam Med. 39 (1): 2–9. doi:10.4082/kjfm.2018.39.1.2. PMC 5788841. PMID 29383205.
- Harvey, S. C. (1980). "Antiseptics and Disinfectants; Fungicides; Ectoparasiticides". In Gilman, A. G.; Goodman, L. S.; Gilman, A. (eds.). Goodman & Gillman's The Pharmacological Basis of Therapeutics (6th ed.). p. 971. ISBN 978-0-02-344720-4.
- "Borates in Pesticides | AMERICAN BORATE COMPANY".
- "Boric Acid General Fact Sheet".
- Birch, Robert G (2013). "Boric acid as a swimming pool buffer" (PDF). The University of Queensland. Retrieved 30 November 2013.
- Düzcükoğlu, H.; Acaroğlu, M. (2009). "Lubrication Properties of Vegetable Oils Combined with Boric Acid and Determination of Their Effects on Wear". Energy Sources, Part A: Recovery, Utilization, and Environmental Effects. 32 (3): 275–285. doi:10.1080/15567030802606053.
- Singh, Harpreet. "Standard equipments". Punjab State Carrom Association. Retrieved 24 September 2009.
- Weingart, George (1947). Pyrotechnics. Chemical Publishing Company. ISBN 978-0820601120.
- "Use of Boric Acid and Borax in Food". www.cfs.gov.hk. Retrieved 22 May 2019.
- Jolly, W. L. (1991). Modern Inorganic Chemistry (2nd ed.). New York: McGraw-Hill. ISBN 978-0-07-112651-9.
- Goodman, L.; Gilman, A.; Brunton, L.; Lazo, J.; Parker, K. (2006). Goodman & Gilman's The Pharmacological Basis of Therapeutics. New York: McGraw Hill.
- Cordia JA, Bal EA, Mak WA and Wils ERJ (2003), Determination of some physico-chemical properties of Optibor EP. Rijswijk, The Netherlands: TNO Prins Maurits Laboratory, report PML 2002-C42rr, GLP, Unpublished, confidential data provided by Bor ax Europe Limited
- Media related to Boric acid at Wikimedia Commons
- Boric Acid Technical Fact Sheet - National Pesticide Information Center
- Boric Acid General Fact Sheet - National Pesticide Information Center
- International Chemical Safety Card 0991
- US EPA Pesticide Reregistration Eligibility Decision
- National Pollutant Inventory - Boron and compounds
- Boric acid at ChemicalLand21
- European Chemicals Agency (ECHA)"New Public Consultation on Eight Potential Substances of Very High Concern" - includes Boric Acid. Closes 22 April 2010
- ChemSub Online: Boric acid