Bothrolysin

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Bothrolysin
Identifiers
EC number 3.4.24.50
CAS number 443890-65-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Bothrolysin (EC 3.4.24.50, Bothrops metalloendopeptidase J, J protease) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Gln4-His, Ser9-His and Ala14-Leu of insulin B chain and Pro-Phe of angiotensin I

This endopeptidase is present in the venom of the jararaca snake (Bothrops jararaca).

References[edit]

  1. ^ Tanizaki, M.M.; Zingali, R.B.; Kawazaki, H.; Imajoh, S.; Yamazaki, S.; Suzuki, K. (1989). "Purification and some characteristics of a zinc metalloprotease from the venom of Bothrops jararaca (jararaca)". Toxicon. 27: 747–755. doi:10.1016/0041-0101(89)90041-x. PMID 2781574. 

External links[edit]