The right brachial plexus with its short branches, viewed from in front.
|From||C5, C6, C7, C8, T1|
|Innervates||Sensory and motor innervation to the upper limb|
|Anatomical terms of neuroanatomy|
The brachial plexus is a network of nerves, running from the spine, formed by the anterior rami of the lower four cervical nerves and first thoracic nerve (C5–C8, T1). The brachial plexus passes through thecervicoaxillary canal in the neck, over the first rib, and into the axilla (armpit region), where it innervates the upper limbs and some neck and shoulder muscles.
- 1 Structure
- 2 Function
- 3 Clinical significance
- 4 Additional images
- 5 References
- 6 External links
The brachial plexus is divided into five roots, three trunks, six divisions, three cords, and five branches. There are five "terminal" branches and numerous other "pre-terminal" or "collateral" branches that leave the plexus at various points along its length. A common structure used to identify part of the brachial plexus in cadaver dissections is the M or W shape made by the musculocutaneous nerve, lateral cord, median nerve, medial cord, and ulnar nerve.
The five roots are the five anterior rami of the spinal nerves, after they have given off their segmental supply to the muscles of the neck. The brachial plexus emerges at five different levels; C5, C6, C7, C8, and T1. C5 and C6 merge to establish the upper trunk, C7 continuously forms the middle trunk, and C8 and T1 merge to establish the lower trunk. Prefixed or postfixed formations in some cases involve C4 or T2, respectively.
These roots merge to form three trunks:
Each trunk then splits in two, to form six divisions:
- anterior divisions of the upper, middle, and lower trunks
- posterior divisions of the upper, middle, and lower trunks
- when observing the body in an anatomical position, the anterior divisions are superficial to the posterior divisions
These six divisions regroup to become the three cords or large fiber bundles. The cords are named by their position with respect to the axillary artery.
- The posterior cord is formed from the three posterior divisions of the trunks (C5-C8,T1)
- The lateral cord is formed from the anterior divisions of the upper and middle trunks (C5-C7)
- The medial cord is simply a continuation of the anterior division of the lower trunk (C8,T1)
The branches are listed below. Most branch from the cords, but a few branch (indicated in italics) directly from earlier structures. The five on the left are considered "terminal branches". There have been several variations reported in the branching pattern but these are very rare.
Bold indicates primary spinal root component of nerve. Italics indicate spinal roots that frequently, but not always, contribute to the nerve.
|roots||dorsal scapular nerve||C4, C5||rhomboid muscles and levator scapulae||-|
|roots||long thoracic nerve||C5, C6, C7||serratus anterior||-|
|roots||branch to phrenic nerve||C5||Diaphragm||-|
|upper trunk||nerve to the subclavius||C5, C6||subclavius muscle||-|
|upper trunk||suprascapular nerve||C5, C6||supraspinatus and infraspinatus||-|
|lateral cord||lateral pectoral nerve||C5, C6, C7||pectoralis major and pectoralis minor (by communicating with the medial pectoral nerve)||-|
|lateral cord||musculocutaneous nerve||C5, C6, C7||coracobrachialis, brachialis and biceps brachii||becomes the lateral cutaneous nerve of the forearm|
|lateral cord||lateral root of the median nerve||C5, C6, C7||fibres to the median nerve||-|
|posterior cord||upper subscapular nerve||C5, C6||subscapularis (upper part)||-|
|posterior cord||thoracodorsal nerve (middle subscapular nerve)||C6, C7, C8||latissimus dorsi||-|
|posterior cord||lower subscapular nerve||C5, C6||subscapularis (lower part ) and teres major||-|
|posterior cord||axillary nerve||C5, C6||anterior branch: deltoid and a small area of overlying skin
posterior branch: teres minor and deltoid muscles
|posterior branch becomes upper lateral cutaneous nerve of the arm|
|posterior cord||radial nerve||C5, C6, C7, C8, T1||triceps brachii, supinator, anconeus, the extensor muscles of the forearm, and brachioradialis||skin of the posterior arm as the posterior cutaneous nerve of the arm. Also superficial branch of radial nerve supplies back of the hand, including the web of skin between the thumb and index finger.|
|medial cord||medial pectoral nerve||C8, T1||pectoralis major and pectoralis minor||-|
|medial cord||medial root of the median nerve||C8, T1||fibres to the median nerve||portions of hand not served by ulnar or radial|
|medial cord||medial cutaneous nerve of the arm||C8, T1||-||front and medial skin of the arm|
|medial cord||medial cutaneous nerve of the forearm||C8, T1||-||medial skin of the forearm|
|medial cord||ulnar nerve||C8, T1||flexor carpi ulnaris, the medial two bellies of flexor digitorum profundus, the intrinsic hand muscles except the thenar muscles and the two most lateral lumbricals||the skin of the medial side of the hand and medial one and a half fingers on the palmar side and medial two and a half fingers on the dorsal side|
The brachial plexus is responsible for cutaneous and muscular innervation of the entire upper limb, with two exceptions: the trapezius muscle innervated by the spinal accessory nerve (CN XI) and an area of skin near the axilla innervated by the intercostobrachial nerve. The brachial plexus communicates through the sympathetic trunk via gray rami communicantes that join the plexus roots.
Brachial plexus injury affects cutaneous sensations and movements in the upper limb. They can be caused by stretching, diseases, and wounds to the lateral cervical region (posterior triangle) of the neck or the axilla. Depending on the location of the injury, the signs and symptoms can range from complete paralysis to anesthesia. Testing the patient's ability to perform movements and comparing it to their normal side is a method to assess the degree of paralysis. A common brachial plexus injury is from a hard landing where the shoulder widely separates from the neck (such as in the case of motorcycle accidents or falling from a tree). These stretches can cause ruptures to the superior portions of the brachial plexus or avulse the roots from the spinal cord. Upper brachial plexus injuries are frequent in newborns when excessive stretching of the neck occurs during delivery. Studies have shown a relationship between birth weight and brachial plexus injuries; however, the number of cesarean deliveries necessary to prevent a single injury is high at most birth weights. For the upper brachial plexus injuries, paralysis occurs in those muscles supplied by C5 and C6 like the deltoid, biceps, brachialis, and brachioradialis. A loss of sensation in the lateral aspect of the upper limb is also common with such injuries. An inferior brachial plexus injury is far less common, but can occur when a person grasps something to break a fall or a baby's upper limb is pulled excessively during delivery. In this case, the short muscles of the hand would be affected and cause the inability to form a full fist position.
To differentiate between pre ganglionic and post ganglionic injury, clinical examination requires that the physician keep the following points in mind. Pre ganglionic injuries cause loss of sensation above the level of the clavicle, pain in an otherwise insensate hand, ipsilateral Horner's syndrome, and loss of function of muscles supplied by branches arising directly from roots—i.e., long thoracic nerve palsy leading to winging of scapula and elevation of ipsilateral diaphragm due to phrenic nerve palsy.
Acute brachial plexus neuritis is a neurological disorder that is characterized by the onset of severe pain in the shoulder region. Additionally, the compression of cords can cause pain radiating down the arm, numbness, paresthesia, erythema, and weakness of the hands. This kind of injury is common for people who have prolonged hyperabduction of the arm when they are performing tasks above their head.
Brachial plexus injuries are injuries that affect the nerves that carry signals from the spine to the shoulder. This can be caused by the shoulder being pushed down and the head being pulled up, which stretches or tears the nerves. Injuries associated with malpositioning commonly affect the brachial plexus nerves, rather than other peripheral nerve groups. Due to the brachial plexus nerves being very sensitive to position, there are very limited ways of preventing such injuries. The most common victims of brachial plexus injuries consist of victims of motor vehicle accidents and newborns.
Motorcyclists who are involved in accidents are very susceptible to brachial plexus injuries due to the nature of the collision. "Brachial plexus injuries were identified in 54 of 4538 patients presenting to a regional trauma facility… Motor vehicle accidents were the most frequent cause overall."
Many of these patients were forced to undergo reconstructive surgery. During physical therapy, the position of the brachial plexus became very important to avoid further damage. "The risk can be reduced by thorough release of the tissues from the inferior surface of the clavicle before mobilization of the fracture fragments." By wearing protective gear, like a helmet, a motorcyclist can help prevent nerve damage after collisions.
Injuries during birth
Brachial Plexus injuries also become an issue during the delivery of newborns. "…there were 80 brachial plexus injuries identified, for an incidence of 1–3 per 1000 live birth." Nerve damage has been connected to birth weight with larger newborns being more susceptible to the injury but it also has to do with the delivery methods. Although very hard to prevent during live birth, doctors must be able to deliver a newborn with precise and gentle movements to decrease chances of injuring the child.
Imaging of the Brachial Plexus can be done effectively by using a higher magnetic strength MRI Scanner like 1.5 T or more. It is impossible to evaluate the brachial plexuses with plain Xray, CT and ultrasound scanning can manage to view the plexuses to an extent; hence MRI is preferred in imaging brachial plexus over other imaging modalities due to its multiplanar capability and the tissue contrast difference between brachial plexus and adjacent vessels. The plexuses are best imaged in coronal and sagittal planes, but axial images give an idea about the nerve roots. Generally, T1 WI and T2 WI images are used in various planes for the imaging; but new sequences like MR Myelolography, Fiesta 3D and T2 cube are also used in addition to the basic sequences to gather more information to evaluate the anatomy more.
- Goel, Shivi; Rustagi, SM; Kumar, A; Mehta, V; Suri, RK (Mar 13, 2014). "Multiple unilateral variations in medial and lateral cords of brachial plexus and their branches". Anatomy & Cell Biology 47 (1): 77–80. doi:10.5115/acb.2014.47.1.77. PMC 3968270. Retrieved 27 May 2015.
- Moore, K.L.; Agur, A.M. (2007). Essential Clinical Anatomy (3rd ed.). Baltimore: Lippincott Williams & Wilkins. pp. 430–1. ISBN 978-0-7817-6274-8.
- Moore, K.L.; Agur, A.M. (2007). Essential Clinical Anatomy (3rd ed.). Baltimore: Lippincott Williams & Wilkins. pp. 434–5. ISBN 978-0-7817-6274-8.
- Ecker, Jeffrey L.; Greenberg, James A.; Norwitz, Errol R.; Nadel, Allan S.; Repke, John T. (1997). "Birth Weight as a Predictor of Brachial Plexus Injury". Obstetrics & Gynecology 89 (5): 643–47. doi:10.1016/S0029-7844(97)00007-0. PMID 9166293.
- Moore, Keith (2006). Clinically Oriented Anatomy. Philadelphia: Lippincott Williams & Wilkins. pp. 778–81. ISBN 0-7817-3639-0.
- http://www.mayoclinic.com/health/brachial-plexus-injury/DS00897/Brachial[full citation needed]
- Cooper, DE; Jenkins, RS; Bready, L; Rockwood Jr, CA (1988). "The prevention of injuries of the brachial plexus secondary to malposition of the patient during surgery". Clinical orthopaedics and related research (228): 33–41. PMID 3342585.
- Jeyaseelan, L.; Singh, V. K.; Ghosh, S.; Sinisi, M.; Fox, M. (2013). "Iatropathic brachial plexus injury: A complication of delayed fixation of clavicle fractures". The Bone & Joint Journal 95–B (1): 106–10. doi:10.1302/0301-620X.95B1.29625. PMID 23307682.
- Midha, Rajiv (1997). "Epidemiology of Brachial Plexus Injuries in a Multitrauma Population". Neurosurgery 40 (6): 1182–8; discussion 1188–9. doi:10.1097/00006123-199706000-00014. PMID 9179891.
- http://www.webmd.com/pain-management/tc/physical-therapy-topic-overview[full citation needed]
|Wikimedia Commons has media related to Brachial plexus.|
- Brachial Plexus and Its Injury| Medchrome
- lesson3brachialplexus at The Anatomy Lesson by Wesley Norman (Georgetown University)
- Brachial Plexus Injury/Illustration, Cincinnati Children's Hospital Medical Center
- Learn the Brachial Plexus in Five Minutes or Less by Daniel S. Romm, M.D. and Dennis A. Chu Chu, M.D. 
- Video of the dissected axilla and Brachial Plexus
- Saladin, Kenneth (2014). Anatomy and Physiology (7th ed.). McGraw-Hill Education. p. 491.
- Kishner, Stephen. "Brachial Plexus Anatomy". Medscape. WebMD. Retrieved 29 Nov 2015.