Britton-Robinson buffer

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

Britton–Robinson buffer (aka BRB aka PEM) is a "universal" pH buffer used for the range pH 2 to pH 12. Universal buffers consist of mixtures of acids of diminishing strength (increasing pKa) so that the change in pH is approximately proportional to the amount of alkali added. It consists of a mixture of 0.04 M H3BO3, 0.04 M H3PO4 and 0.04 M CH3COOH that has been titrated to the desired pH with 0.2 M NaOH. Britton and Robinson also proposed a second formulation that gave an essentially linear pH response to added alkali from pH 2.5 to pH 9.2 (and buffers to pH 12). This mixture consists of 0.0286 M citric acid, 0.0286 M KH2PO4, 0.0286 M H3BO3, 0.0286 M veronal and 0.0286 M HCl titrated with 0.2 M NaOH.

This was invented in 1931 by the English chemist Hubert Thomas Stanley "Kevin" Britton (1892–1960) with the New Zealand chemist Robert Anthony Robinson (1904-1979).[1]


  1. ^ "Journal of the Chemical Society (Resumed)". Royal Society of Chemistry. 1931. Cite journal requires |journal= (help)