Brodmann area 22

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Brodmann area 22
Brodmann Cytoarchitectonics 22.png
Brodmann area 22 (orange)
Human temporal lobe areas.png
Coronal section of the human brain. BA22 is shown in yellow.
NeuroLex IDbirnlex_1753
Anatomical terms of neuroanatomy

Brodmann area 22 is one of Brodmann's area's – cytoarchitecturally defined regions of the brain. It is part of the superior temporal gyrus included in the language processing region known as Wernicke's area.[1]


Brodmann area 22 is the cytoarchitecturally defined posterior superior temporal gyrus on the left side of the brain.[1] In the left hemisphere this area helps with generation and understanding of individual words. On the right side of the brain it helps to discriminate pitch and sound intensity, both of which are necessary to perceive melody and prosody. This part of the brain is active in processing language and is part of Wernicke's area. The other main region included in Wernicke's area is Brodmann area 40, the supramarginal gyrus.

It is bounded rostrally by Brodmann area 38, medially by Brodmann area 42, ventrocaudally by Brodmann area 21, and dorsocaudally by Brodmann area 40, and Brodmann area 39. These cortical regions surround the lower left posterior Sylvian fissure.[1]


Brodmann area 22 is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. It is cytoarchitecturally homologous to the superior temporal area 22 of the human (Brodmann-1909). Distinctive features (Brodmann-1905): compared to Brodmann area 21-1909 the cortical thickness of area 22 is greater; cell density is reduced overall and the internal granular layer (IV) is even less developed with fewer cells; there is no detectable boundary between the internal pyramidal layer (V) and the multiform layer (VI); as in area 21, the ganglion cells of layer V are numerous and are arrayed adjacent to its boundary with layer IV, but they are plumper and more pyramidal in shape; the polymorphic cells of the multiform layer (VI) become gradually more numerous as one goes deeper and gives way to a wide sublayer 6b of fusiform cells as one approaches the boundary of the cortex with the subcortical white matter.


See also[edit]


  1. ^ a b c Binder, JR (15 December 2015). "The Wernicke area: Modern evidence and a reinterpretation". Neurology. 85 (24): 2170–5. doi:10.1212/WNL.0000000000002219. PMID 26567270.

External links[edit]

  • For Neuroanatomy of the superior temporal area 22 visit BrainInfo
  • For Neuroanatomy of Brodmann area 22 visit BrainInfo