Bromazine

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  (Redirected from Bromodiphenhydramine)
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Not to be confused with Promazine.
Bromazine
Bromazine.svg
Clinical data
MedlinePlus a682065
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Bioavailability High
Protein binding 96%
Metabolism Mostly hepatic (CYP-mediated), also renal
Biological half-life 1 to 4 hours
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
ECHA InfoCard 100.003.854
Chemical and physical data
Formula C17H20BrNO
Molar mass 334.251 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Bromazine (trade names Ambrodyl, Ambrodil and others), also known as bromodiphenhydramine, is an antihistamine and anticholinergic.[1] It is a halogenated form of diphenhydramine and in many respects is somewhat stronger than the parent compound. The other three halogenated diphenhydramine derivatives are used in research and chlorodiphenhydramine is also marketed with iododiphenhydramine being a much less common pharmaceutical.

References[edit]

  1. ^ MacLaren, W. R.; Bruff, W. C.; Eisenberg, B. C.; Weiner, H.; Martin, W. H. (1955). "A clinical comparison of carbinoxamine maleate, tripelennamine hydrochloride, and bromodiphenhydramine hydrochloride in treating allergic symptoms". Annals of Allergy. 13 (3): 307–312. PMID 14377226.