Buclizine

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Buclizine
Buclizine.svg
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
ATC code
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
ECHA InfoCard 100.001.317
Chemical and physical data
Formula C28H33ClN2
Molar mass 433.028 g/mol
3D model (JSmol)
Chirality Racemic mixture
 NYesY (what is this?)  (verify)

Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.[1]

In the United Kingdom, buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare at migraine sufferers.[2]

References[edit]

  1. ^ Mostafa GA, Al-Badr AA (2011). "Buclizine". Profiles Drug Subst Excip Relat Methodol. 36: 1–33. doi:10.1016/B978-0-12-387667-6.00001-4. PMID 22469258. 
  2. ^ Behrendt WA, Cserepes J (1985). "Acute toxicity and analgesic action of a combination of buclizine, codeine and paracetamol ('Migraleve') in tablet and suppository form in rats". Pharmatherapeutica. 4 (5): 322–31. PMID 4070325.