Buddleja scordioides is endemic to central Arizona, southeastern New Mexico, southwestern Texas, and the Chihuahua Desert of Mexico, growing amidst xeric thorn-scrub on alkaline soils at elevations of 600 – 2,500 m. The species was first named and described by Kunth in 1818.  
B. scordioides is a weedy dioecious shrub 0.3 – 1.2 m tall with shredding bark. The young branches are subquadrangular and tomentose, bearing small oblong to linear membranaceous grayish-green leaves 1 – 3 cm long by 0.3 – 0.8 cm wide, rugose above, and tomentose on both surfaces. The sage - scented lemon - yellow leafy inflorescences are 2 – 10 cm long, comprising 3 – 15 pairs of sessile clusters, each with 15 – 20 flowers, the corollas 1.5 – 2 mm long. Ploidy: 2n = 38.
The species is not known to be in cultivation.
- Kunth, in Humboldt, Bonpland, and Kunth. (1818). Nov. gen. sp., ed. fol. 2:278 ed. quar. 2:345, t183, 1818.
- Norman, E. M. (2000). Buddlejaceae. Flora Neotropica 81. New York Botanical Garden, USA
- Norman. E.M. Buddlejaceae, Butterfly Bush Family. Journal of the Arizona-Nevada Academy of Science 26:5-6. 1992.