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Bulbous corpuscle

From Wikipedia, the free encyclopedia
Ruffini ending
Nerve ending of Ruffini.
Part ofSkin
Latincorpusculum sensorium fusiforme
TEcorpuscle_by_E5. E5.
Anatomical terminology

The bulbous corpuscle, Ruffini ending or Ruffini corpuscle is a slowly adapting mechanoreceptor located in the cutaneous tissue between the dermal papillae and the hypodermis. It is named after Angelo Ruffini.


Ruffini corpuscles are enlarged dendritic endings with elongated capsules.[1]

Ruffini corpuscle from original slide sent by Ruffini to Sir Charles Sherrington[2]


This spindle-shaped receptor is sensitive to skin stretch, and contributes to the kinesthetic sense of and control of finger position and movement.[3] They are at the highest density around the fingernails where they act in monitoring slippage of objects along the surface of the skin, allowing modulation of grip on an object. [citation needed]

Ruffini corpuscles respond to sustained pressure[4] and show very little adaptation.[5]

Ruffinian endings are located in the deep layers of the skin, and register mechanical deformation within joints, more specifically angle change, with a specificity of up to 2.75 degrees, as well as continuous pressure states. They also act as thermoreceptors that respond for a long time, so in case of deep burn there will be no pain, as these receptors will be burned off.[6]


  1. ^ "8". Ganong's Review of Medical Physiology (23rd ed.). TATA McGraw-Hill Lange. 2010. p. 150. ISBN 978-0-07-067722-7.
  2. ^ Molnár Z, Brown RE., 2010. Insights into the life and work of Sir Charles Sherrington. Nat Rev Neurosci. 11(6):429-36
  3. ^ Mountcastle, Vernon C. (2005). The Sensory Hand: Neural Mechanisms of Somatic Sensation. Harvard University Press. p. 34.
  4. ^ "8". Ganong's Review of Medical Physiology (23rd ed.). TATA McGraw-Hill Lange. 2010. p. 150. ISBN 978-0-07-067722-7.
  5. ^ Arthur c. Guyton; John E. Hall. "47". Guyton & Hall Pocket Companion to Textbook of Medical Physiology (10 ed.). p. 362. ISBN 81-8147-057-5.
  6. ^ Hamilton, Nancy (2008). Kinesiology: Scientific Basis of Human Motion. McGraw-Hill. pp. 76–7.

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