Butaclamol

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Butaclamol
Butaclamol.svg
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEBI
ChEMBL
Chemical and physical data
Formula C25H31NO
Molar mass 361.52 g/mol
3D model (JSmol)

Butaclamol (AY-23,028) is a typical antipsychotic which was never marketed.[1] Sold as the hydrochloride salt for use in research, the compound acts as a dopamine receptor antagonist.[2]

Chemistry[edit]

pKa = 7.15 (uncorrected for ionic strength)[3]

References[edit]

  1. ^ Buckingham, J (1985). Dictionary of organic compounds - Google Books. ISBN 9780412540905. 
  2. ^ http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&N4=D033%7CSIGMA&N25=0&QS=ON&F=SPEC
  3. ^ F. A. Chrzanowski, B. A. McGrogan, B. E. Maryanoff (1985). "The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors." J. Med. Chem. 28 399-400.