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|Molar mass||148.20 g/mol|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.
Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.
- Haloperidol, the most widely used classical antipsychotic drug in this class
- Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment
- Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine)
- Triperidol, a highly potent antipsychotic (100 times more potent than chlorpromazine)
- Melperone, a weakly potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients
- Azaperone, used in veterinary medicine
- Domperidone, a dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself).
- Spiperone (more potent neuroleptic than benperidol)
- Keith Parker; Laurence Brunton; Goodman, Louis Sanford; Lazo, John S.; Gilman, Alfred (2006). Goodman & Gilman's The Pharmacological Basis of Therapeutics (11th ed.). New York: McGraw-Hill. ISBN 0071422803.
- Chronicles of Drug Discovery Vol 2
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