C3a receptor

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C3AR1
Identifiers
Aliases C3AR1, AZ3B, C3AR, HNFAG09, complement component 3a receptor 1
External IDs OMIM: 605246 MGI: 1097680 HomoloGene: 2992 GeneCards: C3AR1
RNA expression pattern
PBB GE C3AR1 209906 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004054
NM_001326475
NM_001326477

NM_009779

RefSeq (protein)

NP_001313404
NP_001313406
NP_004045

NP_033909.1
NP_033909

Location (UCSC) Chr 12: 8.06 – 8.07 Mb Chr 6: 122.85 – 122.86 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in the complement system.[3][4]

The receptor binds to complement component C3a, although there is limited evidence that this receptor also binds C4a in lesser mammals this has yet to be proven true in humans.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Roglic A, Prossnitz ER, Cavanagh SL, Pan Z, Zou A, Ye RD (1996). "cDNA cloning of a novel G protein-coupled receptor with a large extracellular loop structure". Biochim. Biophys. Acta. 1305 (1–2): 39–43. doi:10.1016/0167-4781(95)00209-x. PMID 8605247. 
  4. ^ Ali H, Panettieri RA (2005). "Anaphylatoxin C3a receptors in asthma". Respir. Res. 6: 19. doi:10.1186/1465-9921-6-19. PMC 551592Freely accessible. PMID 15723703. 
  5. ^ Klos A, Wende E, Wareham KJ, Monk PN (2013). "International Union of Pharmacology. LXXXVII. Complement peptide C5a, C4a, and C3a receptors". Pharmacol. Rev. 65 (1): 500–43. doi:10.1124/pr.111.005223. PMID 23383423. 

Further reading[edit]

External links[edit]