CA5B

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CA5B
Identifiers
Aliases CA5B, CA-VB, carbonic anhydrase 5B
External IDs MGI: 1926249 HomoloGene: 21413 GeneCards: CA5B
RNA expression pattern
PBB GE CA5B 207129 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007220

NM_181315

RefSeq (protein)

NP_009151
NP_009151.1

NP_851832.2
NP_851832

Location (UCSC) Chr X: 15.69 – 15.79 Mb Chr X: 163.98 – 164.03 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Carbonic anhydrase 5B, mitochondrial is an enzyme that in humans is encoded by the CA5B gene.[3][4]

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Fujikawa-Adachi K, Nishimori I, Taguchi T, Onishi S (Aug 1999). "Human mitochondrial carbonic anhydrase VB. cDNA cloning, mRNA expression, subcellular localization, and mapping to chromosome x". J Biol Chem. 274 (30): 21228–33. doi:10.1074/jbc.274.30.21228. PMID 10409679. 
  4. ^ a b "Entrez Gene: CA5B carbonic anhydrase VB, mitochondrial". 

External links[edit]

Further reading[edit]