CAB39

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CAB39
Protein CAB39 PDB 1upk.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CAB39, MO25, CGI-66, calcium binding protein 39
External IDs MGI: 107438 HomoloGene: 69212 GeneCards: CAB39
RNA expression pattern
PBB GE CAB39 217873 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001130849
NM_001130850
NM_016289

NM_133781

RefSeq (protein)

NP_001124321
NP_001124322
NP_057373

NP_598542.3
NP_598542

Location (UCSC) Chr 2: 230.71 – 230.82 Mb Chr 1: 85.79 – 85.85 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene.[3]

The protein encoded by this gene associates with STK11 (Serine/Threonine Kinase 11) and STRAD (STE20-Related ADaptor protein).[4] CAB39 enhances formation of STK11/STRAD complexes and stimulates STK11 catalytic activity. CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ "Entrez Gene: CAB39 calcium binding protein 39". 
  4. ^ a b Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR (October 2003). "MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm". EMBO J. 22 (19): 5102–14. doi:10.1093/emboj/cdg490. PMC 204473Freely accessible. PMID 14517248. 

External links[edit]

Further reading[edit]