CACNA1G

From Wikipedia, the free encyclopedia
Jump to: navigation, search
CACNA1G
Identifiers
Aliases CACNA1G, Ca(V)T.1, Cav3.1, NBR13, SCA42, calcium voltage-gated channel subunit alpha1 G
External IDs MGI: 1201678 HomoloGene: 22544 GeneCards: 8913
Genetically Related Diseases
Disease Name References
Alzheimer's disease
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001112813
NM_001177888
NM_001177890
NM_009783

RefSeq (protein)

n/a

Location (UCSC) Chr 17: 50.56 – 50.63 Mb Chr 11: 94.41 – 94.47 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Calcium channel, voltage-dependent, T type, alpha 1G subunit, also known as CACNA1G or Cav3.1 is a protein which in humans is encoded by the CACNA1G gene.[4][5][6]

Function[edit]

Voltage-dependent calcium channels can be distinguished based on their voltage-dependence, deactivation, and single-channel conductance. Low-voltage-activated calcium channels are referred to as 'T' type because their currents are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing.[4]

Interactive pathway map[edit]

Click on genes, proteins and metabolites below to link to respective Wikipedia articles. [§ 1]

[[File:
NicotineActivityonChromaffinCells_WP1603 Go to article go to article Go to article Go to article Go to article Go to article go to article go to article Go to article Go to article go to article Go to article Go to article
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
[[
]]
NicotineActivityonChromaffinCells_WP1603 Go to article go to article Go to article Go to article Go to article Go to article go to article go to article Go to article Go to article go to article Go to article Go to article
|{{{bSize}}}px|alt=Nicotine Activity on Chromaffin Cells edit]]
Nicotine Activity on Chromaffin Cells edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "NicotineActivityonChromaffinCells_WP1603". 

See also[edit]

References[edit]

  1. ^ "chibi.ubc.ca/Gemma/phenotypes.html?phenotypeUrlId=DOID_10652&geneId=187702". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ a b "Entrez Gene: CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit". 
  5. ^ Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M, Lee JH (February 1998). "Molecular characterization of a neuronal low-voltage-activated T-type calcium channel". Nature. 391 (6670): 896–900. doi:10.1038/36110. PMID 9495342. 
  6. ^ Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J (December 2005). "International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels". Pharmacol. Rev. 57 (4): 411–25. doi:10.1124/pr.57.4.5. PMID 16382099. 

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.