CALM2

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CALM2
Protein CALM2 PDB 1a29.png
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases CALM2, CAMII, PHKD, PHKD2, LQT15, caM, calmodulin 2 (phosphorylase kinase, delta)
External IDs HomoloGene: 134804 GeneCards: CALM2
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001743
NM_001305624
NM_001305625
NM_001305626

n/a

RefSeq (protein)

n/a

Location (UCSC) Chr 19: 90.4 – 90.41 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Calmodulin 2 is a protein that in humans is encoded by the CALM2 gene.[2][3]

Clinical significance[edit]

Mutations in CALM2 are associated to cardiac arrhythmias .[4]

Interactions[edit]

CALM2 has been shown to interact with AKAP9.[5][6]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Entrez Gene: CALM2 Calmodulin 2 (phosphorylase kinase, delta)". 
  3. ^ SenGupta B, Friedberg F, Detera-Wadleigh SD (December 1987). "Molecular analysis of human and rat calmodulin complementary DNA clones. Evidence for additional active genes in these species". J. Biol. Chem. 262 (34): 16663–70. PMID 2445749. 
  4. ^ Makita N, Yagihara N, Crotti L, Johnson CN, Beckmann BM, Roh MS, Shigemizu D, Lichtner P, Ishikawa T, Aiba T, Homfray T, Behr ER, Klug D, Denjoy I, Mastantuono E, Theisen D, Tsunoda T, Satake W, Toda T, Nakagawa H, Tsuji Y, Tsuchiya T, Yamamoto H, Miyamoto Y, Endo N, Kimura A, Ozaki K, Motomura H, Suda K, Tanaka T, Schwartz PJ, Meitinger T, Kääb S, Guicheney P, Shimizu W, Bhuiyan ZA, Watanabe H, Chazin WJ, George AL (2014). "Novel calmodulin mutations associated with congenital arrhythmia susceptibility". Circ Cardiovasc Genet. 7 (4): 466–74. doi:10.1161/CIRCGENETICS.113.000459. PMC 4140998Freely accessible. PMID 24917665. 
  5. ^ Takahashi M, Yamagiwa A, Nishimura T, Mukai H, Ono Y (Sep 2002). "Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex". Mol. Biol. Cell. 13 (9): 3235–45. doi:10.1091/mbc.E02-02-0112. PMC 124155Freely accessible. PMID 12221128. 
  6. ^ Berchtold MW, Egli R, Rhyner JA, Hameister H, Strehler EE (May 1993). "Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3". Genomics. 16 (2): 461–5. doi:10.1006/geno.1993.1211. PMID 8314583. 

External links[edit]

Further reading[edit]