CALN1

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CALN1
Identifiers
Aliases CALN1, CABP8, calneuron 1
External IDs MGI: 2155987 HomoloGene: 10966 GeneCards: CALN1
Genetically Related Diseases
amyotrophic lateral sclerosis[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001017440
NM_031468

NM_021371
NM_181045

RefSeq (protein)

NP_001017440
NP_113656

NP_067346.1
NP_851388.1
NP_067346
NP_851388

Location (UCSC) Chr 7: 71.78 – 72.45 Mb Chr 5: 130.37 – 130.85 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene.[4][5] Alternative splicing results in multiple transcript variants.[5]

Function[edit]

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites.[6]

References[edit]

  1. ^ "Diseases that are genetically associated with CALN1 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Molecular Genetics and Metabolism. 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509. 
  5. ^ a b "Entrez Gene: CALN1 calneuron 1". 
  6. ^ McCue HV, Haynes LP, Burgoyne RD (Aug 2010). "The diversity of calcium sensor proteins in the regulation of neuronal function". Cold Spring Harbor Perspectives in Biology. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMC 2908765Freely accessible. PMID 20668007. 

External links[edit]

Further reading[edit]