CAMK2D

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CAMK2D
Protein CAMK2D PDB 2VN9.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CAMK2D, CAMKD, calcium/calmodulin dependent protein kinase II delta
External IDs MGI: 1341265 HomoloGene: 55561 GeneCards: 817
Genetically Related Diseases
Disease Name References
chronic lymphocytic leukemia
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)

NP_001020609.1
NP_001020610.1
NP_001280592.1
NP_001280593.1
NP_076302.1

Location (UCSC) Chr 4: 113.45 – 113.76 Mb Chr 3: 126.6 – 126.85 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Calcium/calmodulin-dependent protein kinase type II delta chain is an enzyme that in humans is encoded by the CAMK2D gene.[4]

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca2+/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Four alternatively spliced transcript variants that encode three different isoforms have been characterized to date. Distinct isoforms of this chain have different expression patterns.[4]

References[edit]

Further reading[edit]