CAMK4

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CAMK4
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CAMK4, CaMK IV, CaMK-GR, IV, caMK, calcium/calmodulin-dependent protein kinase IV, calcium/calmodulin dependent protein kinase IV
External IDs MGI: 88258 HomoloGene: 100780 GeneCards: CAMK4
Genetically Related Diseases
Alzheimer's disease[1]
RNA expression pattern
PBB GE CAMK4 210349 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001744
NM_001323374
NM_001323375
NM_001323376
NM_001323377

NM_009793

RefSeq (protein)

NP_001310303
NP_001310304
NP_001310305
NP_001310306
NP_001735

n/a

Location (UCSC) Chr 5: 111.22 – 111.49 Mb Chr 18: 32.94 – 33.2 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene.[4]

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.[5]

References[edit]

  1. ^ "Diseases that are genetically associated with CAMK4 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Sikela JM, Law ML, Kao FT, Hartz JA, Wei Q, Hahn WE (Mar 1989). "Chromosomal localization of the human gene for brain Ca2+/calmodulin-dependent protein kinase type IV". Genomics. 4 (1): 21–7. doi:10.1016/0888-7543(89)90309-1. PMID 2536634. 
  5. ^ "Entrez Gene: CAMK4 calcium/calmodulin-dependent protein kinase IV". 

External links[edit]

Further reading[edit]