CAMK4

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CAMK4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCAMK4, CaMK IV, CaMK-GR, IV, caMK, calcium/calmodulin-dependent protein kinase IV, calcium/calmodulin dependent protein kinase IV, CaMKIV
External IDsOMIM: 114080 MGI: 88258 HomoloGene: 100780 GeneCards: CAMK4
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for CAMK4
Genomic location for CAMK4
Band5q22.1Start111,223,653 bp[1]
End111,494,886 bp[1]
RNA expression pattern
PBB GE CAMK4 210349 at tn.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001744
NM_001323374
NM_001323375
NM_001323376
NM_001323377

NM_009793

RefSeq (protein)

NP_001310303
NP_001310304
NP_001310305
NP_001310306
NP_001735

NP_033923

Location (UCSC)Chr 5: 111.22 – 111.49 MbChr 18: 32.93 – 33.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene.[5]

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase (CAMK) subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons, and male germ cells.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000152495 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038128 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sikela JM, Law ML, Kao FT, Hartz JA, Wei Q, Hahn WE (Mar 1989). "Chromosomal localization of the human gene for brain Ca2+/calmodulin-dependent protein kinase type IV". Genomics. 4 (1): 21–7. doi:10.1016/0888-7543(89)90309-1. PMID 2536634.
  6. ^ "Entrez Gene: CAMK4 calcium/calmodulin-dependent protein kinase IV".

Further reading[edit]

External links[edit]