From Wikipedia, the free encyclopedia
Jump to: navigation, search
Calcium/calmodulin-dependent protein kinase IV
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols CAMK4 ; CaMK IV; CaMK-GR; IV; caMK
External IDs OMIM114080 MGI88258 HomoloGene100780 ChEMBL: 2494 GeneCards: CAMK4 Gene
EC number
RNA expression pattern
PBB GE CAMK4 210349 at tn.png
More reference expression data
Species Human Mouse
Entrez 814 12326
Ensembl ENSG00000152495 ENSMUSG00000038128
UniProt Q16566 Q8BGR3
RefSeq (mRNA) NM_001744 NM_009793
RefSeq (protein) NP_001735 NP_033923
Location (UCSC) Chr 5:
111.22 – 111.49 Mb
Chr 18:
32.94 – 33.2 Mb
PubMed search [1] [2]

Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene.[1]

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.[2]


  1. ^ Sikela JM, Law ML, Kao FT, Hartz JA, Wei Q, Hahn WE (Mar 1989). "Chromosomal localization of the human gene for brain Ca2+/calmodulin-dependent protein kinase type IV". Genomics 4 (1): 21–7. doi:10.1016/0888-7543(89)90309-1. PMID 2536634. 
  2. ^ "Entrez Gene: CAMK4 calcium/calmodulin-dependent protein kinase IV". 

Further reading[edit]