CCL4 is a major HIV-suppressive factor produced by CD8+ T cells.
Perforin-low memory CD8+ T cells that normally synthesize MIP-1-beta.
CCL4 is produced by: monocytes, B cells, T cells, fibroblasts, endothelial cells, and epithelial cells.
Concentration of this chemokine has been shown to be inversely related with MicroRNA-125b. Concentration of CCL4 within the body increases with age, which may cause chronic inflammation and liver damage.
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