CCNF

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CCNF may also mean Canonical conjunctive normal form in Boolean algebra.
CCNF
Identifiers
Aliases CCNF, FBX1, FBXO1, cyclin F
External IDs MGI: 102551 HomoloGene: 1335 GeneCards: CCNF
RNA expression pattern
PBB GE CCNF 204827 s at fs.png

PBB GE CCNF 204826 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001761
NM_001323538

NM_007634

RefSeq (protein)

NP_001310467
NP_001752

NP_031660.3
NP_031660

Location (UCSC) Chr 16: 2.43 – 2.46 Mb Chr 17: 24.22 – 24.25 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

G2/mitotic-specific cyclin-F is a protein that in humans is encoded by the CCNF gene.[3][4]

This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Kraus B, Pohlschmidt M, Leung AL, Germino GG, Snarey A, Schneider MC, Reeders ST, Frischauf AM (Apr 1995). "A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1)". Genomics. 24 (1): 27–33. doi:10.1006/geno.1994.1578. PMID 7896286. 
  4. ^ a b "Entrez Gene: CCNF cyclin F". 

External links[edit]

Further reading[edit]