CCP110

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CCP110
Identifiers
Aliases CCP110, CP110, Cep110, centriolar coiled-coil protein 110kDa, centriolar coiled-coil protein 110
External IDs MGI: 2141942 HomoloGene: 8810 GeneCards: CCP110
RNA expression pattern
PBB GE CP110 204662 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_182995

RefSeq (protein)

NP_892040.1
NP_892040

Location (UCSC) Chr 16: 19.52 – 19.55 Mb Chr 7: 118.71 – 118.74 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Centriolar coiled-coil protein of 110 kDa also known as centrosomal protein of 110 kDa or CP110 is a protein that in humans is encoded by the CCP110 gene. It is a cell cycle-dependent CDK substrate and regulates centrosome duplication.[3][4] CP110 suppresses a cilia assembly program.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Chen Z, Indjeian VB, McManus M, Wang L, Dynlacht BD (September 2002). "CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells". Dev. Cell. 3 (3): 339–50. doi:10.1016/S1534-5807(02)00258-7. PMID 12361598. 
  4. ^ Li J, D'Angiolella V, Seeley ES, Kim S, Kobayashi T, Fu W, Campos EI, Pagano M, Dynlacht BD (March 2013). "USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110". Nature. 495 (7440): 255–9. doi:10.1038/nature11941. PMID 23486064. 
  5. ^ Spektor A, Tsang WY, Khoo D, Dynlacht BD (August 2007). "Cep97 and CP110 suppress a cilia assembly program". Cell. 130 (4): 678–90. doi:10.1016/j.cell.2007.06.027. PMID 17719545. 

External links[edit]

Further reading[edit]