CCT6B

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CCT6B
Identifiers
Aliases CCT6B, CCT-zeta-2, CCTZ-2, Cctz2, TCP-1-zeta-2, TSA303, chaperonin containing TCP1 subunit 6B
External IDs MGI: 1329013 HomoloGene: 55978 GeneCards: CCT6B
RNA expression pattern
PBB GE CCT6B 206587 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001193529
NM_001193530
NM_006584

NM_001291242
NM_009839

RefSeq (protein)

NP_001180458
NP_001180459
NP_006575

NP_033969.2
NP_001278171
NP_033969

Location (UCSC) Chr 17: 34.93 – 34.98 Mb Chr 11: 82.72 – 82.76 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

T-complex protein 1 subunit zeta-2 is a protein that in humans is encoded by the CCT6B gene.[3][4][5]

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ozaki K, Kuroki T, Hayashi S, Nakamura Y (Jan 1997). "Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method". Genomics. 36 (2): 316–9. doi:10.1006/geno.1996.0467. PMID 8812458. 
  4. ^ Kubota H, Hynes GM, Kerr SM, Willison KR (Feb 1997). "Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1". FEBS Lett. 402 (1): 53–6. doi:10.1016/S0014-5793(96)01501-3. PMID 9013858. 
  5. ^ a b "Entrez Gene: CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)". 

External links[edit]

Further reading[edit]