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CD164 molecule, sialomucin
Symbols CD164 ; MGC-24; MUC-24; endolyn
External IDs OMIM603356 MGI1859568 HomoloGene38129 GeneCards: CD164 Gene
Species Human Mouse
Entrez 8763 53599
Ensembl ENSG00000135535 ENSMUSG00000019818
UniProt Q04900 Q9R0L9
RefSeq (mRNA) NM_001142401 NM_016898
RefSeq (protein) NP_001135873 NP_058594
Location (UCSC) Chr 6:
109.37 – 109.38 Mb
Chr 10:
41.52 – 41.53 Mb
PubMed search [1] [2]

Sialomucin core protein 24 also known as endolyn or CD164 (cluster of differentiation 164) is a protein that in humans is encoded by the CD164 gene.[1][2] CD164 functions as a cell adhesion molecule.

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play two key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor.[1]


  1. ^ a b Watt SM, Bühring HJ, Rappold I, Chan JY, Lee-Prudhoe J, Jones T, Zannettino AC, Simmons PJ, Doyonnas R, Sheer D, Butler LH (August 1998). "CD164, a novel sialomucin on CD34(+) and erythroid subsets, is located on human chromosome 6q21". Blood 92 (3): 849–66. PMID 9680353. 
  2. ^ Zannettino AC, Bühring HJ, Niutta S, Watt SM, Benton MA, Simmons PJ (October 1998). "The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis". Blood 92 (8): 2613–28. PMID 9763543. 

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