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AliasesCD164, MGC-24, MUC-24, endolyn, DFNA66, CD164 molecule, MGC-24v
External IDsOMIM: 603356 MGI: 1859568 HomoloGene: 38129 GeneCards: CD164
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for CD164
Genomic location for CD164
Band6q21Start109,366,514 bp[1]
End109,382,467 bp[1]
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC)Chr 6: 109.37 – 109.38 MbChr 10: 41.52 – 41.53 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

Sialomucin core protein 24 also known as endolyn or CD164 (cluster of differentiation 164) is a protein that in humans is encoded by the CD164 gene.[5][6] CD164 functions as a cell adhesion molecule.

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play two key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor.[5]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135535 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019818 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b Watt SM, Bühring HJ, Rappold I, Chan JY, Lee-Prudhoe J, Jones T, Zannettino AC, Simmons PJ, Doyonnas R, Sheer D, Butler LH (August 1998). "CD164, a novel sialomucin on CD34(+) and erythroid subsets, is located on human chromosome 6q21". Blood. 92 (3): 849–66. PMID 9680353.
  6. ^ Zannettino AC, Bühring HJ, Niutta S, Watt SM, Benton MA, Simmons PJ (October 1998). "The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis". Blood. 92 (8): 2613–28. PMID 9763543.

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