CD200

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CD200
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCD200, CD200 molecule, MOX1, MOX2, MRC, OX-2
External IDsMGI: 1196990 HomoloGene: 4344 GeneCards: CD200
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for CD200
Genomic location for CD200
Band3q13.2Start112,332,347 bp[1]
End112,362,812 bp[1]
RNA expression pattern
PBB GE CD200 209583 s at fs.png

PBB GE CD200 209582 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_010818
NM_001358443

RefSeq (protein)

NP_001004196
NP_001305755
NP_001305757
NP_001305759
NP_005935

n/a

Location (UCSC)Chr 3: 112.33 – 112.36 MbChr 16: 45.38 – 45.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

OX-2 membrane glycoprotein, also named CD200 (Cluster of Differentiation 200)[5] is a human protein encoded by the CD200 gene.[6]

The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.[6]

See also[edit]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.