CD24

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CD24
Identifiers
Aliases CD24, CD24A, CD24 molecule
External IDs OMIM: 600074 GeneCards: 100133941
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001291737
NM_001291738
NM_001291739
NM_013230

n/a

RefSeq (protein)

NP_001278666.1
NP_001278667.1
NP_037362.1

n/a

Location (UCSC) Chr 6: 106.97 – 106.98 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Signal transducer CD24 also known as cluster of differentiation 24 or heat stable antigen CD24 (HSA) is a protein that in humans is encoded by the CD24 gene.[1] CD24 is a cell adhesion molecule.

Function[edit]

CD24 is a glycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and in many B cells. The encoded protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. CD24 gene is found on chromosome 6 (6q21) An alignment of this gene's sequence finds genomic locations with similarity on chromosomes 1p36, 3p26, 15q21.3, 20q11.2 and Yq11.222. Whether transcription, and corresponding translation, occurs at each of these other genomic locations needs to be experimentally determined (source: NCBI).

References[edit]

  1. ^ Hough MR, Rosten PM, Sexton TL, Kay R, Humphries RK (July 1994). "Mapping of CD24 and homologous sequences to multiple chromosomal loci". Genomics 22 (1): 154–61. doi:10.1006/geno.1994.1356. PMID 7959762. 

Further reading[edit]

External links[edit]