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CD3g molecule, gamma (CD3-TCR complex)
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols CD3G ; CD3-GAMMA; IMD17; T3G
External IDs OMIM186740 MGI88333 HomoloGene55 GeneCards: CD3G Gene
RNA expression pattern
PBB GE CD3G 206804 at tn.png
More reference expression data
Species Human Mouse
Entrez 917 12502
Ensembl ENSG00000160654 ENSMUSG00000002033
UniProt P09693 P11942
RefSeq (mRNA) NM_000073 NM_009850
RefSeq (protein) NP_000064 NP_033980
Location (UCSC) Chr 11:
118.34 – 118.36 Mb
Chr 9:
44.97 – 44.98 Mb
PubMed search [1] [2]

T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene.

T cell antigen receptor (TCR) is associated on the T cell surface with a complex of protein called CD3. CD3G (gamma chain) is one of the four peptides (gamma, delta, epsilon and zeta) that form CD3. Defects in CD3G are associated with T cell immunodeficiency.[1]

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Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.