CD69

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CD69
Protein CD69 PDB 1e87.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CD69, AIM, BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3, CD69 molecule
External IDs MGI: 88343 HomoloGene: 128584 GeneCards: 969
Genetically Related Diseases
Disease Name References
diabetes mellitus type 1
RNA expression pattern
PBB GE CD69 209795 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001781

NM_001033122

RefSeq (protein)

NP_001772.1

NP_001028294.1

Location (UCSC) Chr 12: 9.75 – 9.76 Mb Chr 6: 129.27 – 129.28 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

CD69 (Cluster of Differentiation 69) is a human transmembrane C-Type lectin protein encoded by the CD69 gene.

The activation of T lymphocytes and Natural Killer (NK) Cells, both in vivo and in vitro, induces expression of CD69. This molecule, which appears to be the earliest inducible cell surface glycoprotein acquired during lymphoid activation, is involved in lymphocyte proliferation and functions as a signal-transmitting receptor in lymphocytes, including natural killer (NK) cells, and platelets (Cambiaggi et al., 1992) [supplied by OMIM].[1]

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