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Cyclin-dependent kinase-like 2 (CDC2-related kinase)
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols CDKL2 ; KKIAMRE; P56
External IDs OMIM603442 MGI1858227 HomoloGene55793 ChEMBL: 5728 GeneCards: CDKL2 Gene
EC number
RNA expression pattern
PBB GE CDKL2 207073 at tn.png
More reference expression data
Species Human Mouse
Entrez 8999 53886
Ensembl ENSG00000138769 ENSMUSG00000029403
UniProt Q92772 Q9QUK0
RefSeq (mRNA) NM_003948 NM_001276315
RefSeq (protein) NP_003939 NP_001263244
Location (UCSC) Chr 4:
75.58 – 75.63 Mb
Chr 5:
92.01 – 92.04 Mb
PubMed search [1] [2]

Cyclin-dependent kinase-like 2 is an enzyme that in humans is encoded by the CDKL2 gene.[1][2]

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.[2]


  1. ^ Taglienti CA, Wysk M, Davis RJ (Feb 1997). "Molecular cloning of the epidermal growth factor-stimulated protein kinase p56 KKIAMRE". Oncogene 13 (12): 2563–74. PMID 9000130. 
  2. ^ a b "Entrez Gene: CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase)". 

Further reading[edit]