CENPC1

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CENPC
Identifiers
AliasesCENPC, CENP-C, CENPC1, MIF2, hcp-4, centromere protein C
External IDsMGI: 99700 HomoloGene: 1371 GeneCards: CENPC
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for CENPC
Genomic location for CENPC
Band4q13.2Start67,468,762 bp[1]
End67,545,503 bp[1]
RNA expression pattern
PBB GE CENPC1 204739 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001812
NM_001362481

NM_007683
NM_001345902
NM_001345903
NM_001345904

RefSeq (protein)

NP_001803
NP_001349410

NP_001332831
NP_001332832
NP_001332833
NP_031709

Location (UCSC)Chr 4: 67.47 – 67.55 MbChr 5: 86.01 – 86.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Centromere protein C 1 is a protein that in humans is encoded by the CENPC1 gene.[5][6]

Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000145241 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029253 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ McKay S, Thomson E, Cooke H (Dec 1994). "Sequence homologies and linkage group conservation of the human and mouse Cenpc genes". Genomics. 22 (1): 36–40. doi:10.1006/geno.1994.1342. PMID 7959789.
  6. ^ a b "Entrez Gene: CENPC1 centromere protein C 1".

External links[edit]

Further reading[edit]