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Centromere protein C
Symbols CENPC ; CENP-C; CENPC1; MIF2; hcp-4
External IDs OMIM117141 MGI99700 HomoloGene1371 GeneCards: CENPC Gene
RNA expression pattern
PBB GE CENPC1 204739 at tn.png
More reference expression data
Species Human Mouse
Entrez 1060 12617
Ensembl ENSG00000145241 ENSMUSG00000029253
UniProt Q03188 P49452
RefSeq (mRNA) NM_001812 NM_007683
RefSeq (protein) NP_001803 NP_031709
Location (UCSC) Chr 4:
67.47 – 67.55 Mb
Chr 5:
86.01 – 86.07 Mb
PubMed search [1] [2]

Centromere protein C 1 is a protein that in humans is encoded by the CENPC1 gene.[1][2]

Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.[2]


  1. ^ McKay S, Thomson E, Cooke H (Dec 1994). "Sequence homologies and linkage group conservation of the human and mouse Cenpc genes". Genomics 22 (1): 36–40. doi:10.1006/geno.1994.1342. PMID 7959789. 
  2. ^ a b "Entrez Gene: CENPC1 centromere protein C 1". 

Further reading[edit]