CEP120

From Wikipedia, the free encyclopedia
Jump to: navigation, search
CEP120
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CEP120, CCDC100, SRTD13, centrosomal protein 120
External IDs MGI: 2147298 HomoloGene: 27415 GeneCards: CEP120
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001166226
NM_153223

NM_178686

RefSeq (protein)

NP_001159698
NP_694955

NP_848801.2
NP_848801

Location (UCSC) Chr 5: 123.34 – 123.42 Mb Chr 18: 53.68 – 53.74 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Centrosomal protein of 120 kDa (Cep120), also known as coiled-coil domain-containing protein 100, is a protein that in humans is encoded by the CEP120 gene.[3][4]

Function[edit]

This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects.[3]

References[edit]

External links[edit]

Further reading[edit]