CEP135

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CEP135
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CEP135, CEP4, KIAA0635, MCPH8, centrosomal protein 135
External IDs MGI: 2681869 HomoloGene: 45709 GeneCards: CEP135
RNA expression pattern
PBB GE CEP135 206003 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014645
NM_025009

NM_199032

RefSeq (protein)

NP_079285

NP_950197.1
NP_950197

Location (UCSC) Chr 4: 55.95 – 56.03 Mb Chr 5: 76.59 – 76.65 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Centrosomal protein of 135 kDa is a protein that in humans is encoded by the CEP135 gene.[3][4][5] It is part of the centrosome throughout the cell cycle, being distributed in the pericentriolar material.[6] CEP135 is required for the centriolar localization of CEP250.[7]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811. 
  4. ^ Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M (Dec 2003). "Proteomic characterization of the human centrosome by protein correlation profiling". Nature. 426 (6966): 570–4. doi:10.1038/nature02166. PMID 14654843. 
  5. ^ "Entrez Gene: CEP135 centrosomal protein 135kDa". 
  6. ^ Ohta T, Essner R, Ryu JH, Palazzo RE, Uetake Y, Kuriyama R (January 2002). "Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells". J. Cell Biol. 156 (1): 87–99. doi:10.1083/jcb.200108088. PMC 2173569Freely accessible. PMID 11781336. 
  7. ^ Kim K, Lee S, Chang J, Rhee K (December 2008). "A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization". Exp. Cell Res. 314 (20): 3692–700. doi:10.1016/j.yexcr.2008.09.016. PMID 18851962. 

External links[edit]

Further reading[edit]