CEP70

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CEP70
Identifiers
Aliases CEP70, BITE, centrosomal protein 70
External IDs MGI: 1915371 HomoloGene: 11387 GeneCards: CEP70
RNA expression pattern
PBB GE CEP70 219036 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_023873

RefSeq (protein)

NP_076362.2
NP_076362

Location (UCSC) Chr 3: 138.49 – 138.59 Mb Chr 9: 99.24 – 99.3 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Centrosomal protein of 70 kDa is a protein that in humans is encoded by the CEP70 gene.[3][4] The protein interacts with γ-tubulin through its coiled coil domains to localize at the centrosome. CEP70 is involved in organizing microtubules in interphase cells and is required for proper organization and orientation of the mitotic spindle.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M (Dec 2003). "Proteomic characterization of the human centrosome by protein correlation profiling". Nature. 426 (6966): 570–4. doi:10.1038/nature02166. PMID 14654843. 
  4. ^ "Entrez Gene: CEP70 centrosomal protein 70kDa". 
  5. ^ Shi X, Sun X, Liu M, Li D, Aneja R, Zhou J (September 2011). "CEP70 protein interacts with γ-tubulin to localize at the centrosome and is critical for mitotic spindle assembly". J. Biol. Chem. 286 (38): 33401–8. doi:10.1074/jbc.M111.252262. PMC 3190865Freely accessible. PMID 21795687. 

External links[edit]

Further reading[edit]