Centrin 1

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CETN1
Protein CETN1 PDB 1m39.png
Identifiers
Aliases CETN1, CEN1, CETN, centrin 1
External IDs MGI: 1347086 HomoloGene: 105668 GeneCards: CETN1
RNA expression pattern
PBB GE CETN1 207209 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004066

NM_007593

RefSeq (protein)

NP_004057

NP_031619.3
NP_031619

Location (UCSC) Chr 18: 0.58 – 0.58 Mb Chr 18: 9.62 – 9.62 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Centrin-1 is a protein that in humans is encoded by the CETN1 gene.[3][4] It belongs to the centrin family of proteins.

The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Errabolu R, Sanders MA, Salisbury JL (Jun 1994). "Cloning of a cDNA encoding human centrin, an EF-hand protein of centrosomes and mitotic spindle poles". J Cell Sci. 107. ( Pt 1): 9–16. PMID 8175926. 
  4. ^ a b "Entrez Gene: CETN1 centrin, EF-hand protein, 1". 

External links[edit]

Further reading[edit]